Evidence map›Paper›PMID 42236649›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2026

Reciprocal Relationship Between Cardiovascular Risk and Attainment of Blood Pressure and Cholesterol Targets in Users of a Mobile Health App.

Fabian Starnecker, Johannes Krefting, Leon Nissen, Marius Schwab, Marko Jovanovic, Sinann Al Najem, Moritz von Scheidt, Stephan Jonas, Heribert Schunkert, Lara Marie Reimer

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Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

10 authors.

Fabian StarneckerDepartment of Cardiovascular Diseases, School of Medicine and Health, German Heart Centre Munich, TUM University Hospital, Technical University of Munich, Lazarettstr. 36, 80636, Munich, Germany. fabian.starnecker@tum.de.ORCID http://orcid.org/0000-0001-9850-4239
Johannes KreftingDepartment of Cardiovascular Diseases, School of Medicine and Health, German Heart Centre Munich, TUM University Hospital, Technical University of Munich, Lazarettstr. 36, 80636, Munich, Germany.
Leon NissenInstitute for Digital Medicine, University Hospital Bonn, Bonn, Germany.
Marius SchwabDepartment of Cardiovascular Diseases, School of Medicine and Health, German Heart Centre Munich, TUM University Hospital, Technical University of Munich, Lazarettstr. 36, 80636, Munich, Germany.
Marko JovanovicInstitute for Digital Medicine, University Hospital Bonn, Bonn, Germany.
Sinann Al NajemGerman Heart Foundation (Deutsche Herzstiftung, e.V.), Frankfurt, Germany.
Moritz von ScheidtDepartment of Cardiovascular Diseases, School of Medicine and Health, German Heart Centre Munich, TUM University Hospital, Technical University of Munich, Lazarettstr. 36, 80636, Munich, Germany.
Stephan JonasInstitute for Digital Medicine, University Hospital Bonn, Bonn, Germany.
Heribert SchunkertDepartment of Cardiovascular Diseases, School of Medicine and Health, German Heart Centre Munich, TUM University Hospital, Technical University of Munich, Lazarettstr. 36, 80636, Munich, Germany.
Lara Marie ReimerInstitute for Digital Medicine, University Hospital Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVoluntary users of mobile health (mHealth) apps indicate an interest in lowering cardiovascular disease (CVD) risk. It is unclear by which extent blood pressure (BP) or cholesterol treatment targets are achieved in such individuals.

aimThis study aimed to evaluate the attainment of guideline-recommended BP and cholesterol targets across different CVD risk categories among mHealth app users.

methodsWe grouped users of the publicly available German mHealth app HerzFit, who donated their data for scientific evaluations, into individuals with "low-to-moderate risk", "high risk" and "very high risk" of future CVD events. Risk factor control was assessed according to presence of antihypertensive or cholesterol-lowering treatment and achievement of guideline-recommended BP and cholesterol treatment targets.

resultsIndividual data sets from 1,230 HerzFit users without CVD who provided BP and cholesterol levels were used for the analysis. 471 users were categorized as low (-to-moderate) risk (38.3%), 595 as high risk (48.4%), and 164 as very high risk (13.3%). Antihypertensive treatment was reported in 36.9% of low-risk individuals, 58.2% of high-risk individuals (p<0.001 vs. low), and 59.1% of very high-risk individuals (p<0.001 vs. low). Cholesterol-lowering therapy was present in 29.3%, 41.7% (p<0.001 vs. low), and 40.9% (p=0.01 vs. low), respectively. Use of high-intensity statins (9%) and statin-ezetimibe combinations (5%) was low across all risk groups. BP control was achieved in 79.0% of low-risk individuals, 65.4% of high-risk individuals (P<0.001 vs. low) and 48.2% of very high-risk individuals (p<0.001 vs. low). Respective numbers for cholesterol control were 30.4%, 12.8% (p<0.001 vs. low) and 11.0% (p<0.001 vs. low).

conclusionsDespite being treated more frequently, individuals at high or very-high risk achieved poorer BP and cholesterol control compared to individuals at low-to-moderate risk. Thus, effective medications are particularly underutilized in individuals at high risk for future CVD events, despite an expressed interest in management of cardiovascular health.

Indexed as

Cardiovascular diseaseHypercholesterolemiaHypertensionmHealth appPreventionRisk factor

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.