Evidence map›Paper›PMID 42236634›Full record

ArticleEJNMMI radiopharmacy and chemistry2026

Design and development of a semi-automated solid target assembly for the indigenous production of medical radioisotopes in the PETrace-800 cyclotron.

Kanchan Kushwaha, Kavindra Pathak, Tejinder P Sabharwal, Sunil Kamble, Arpit Mitra, Sudeep Sahu, Pravind Maletha, Nand Kishore Prasad, Manish Kumar, Sharmila Banerjee

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Article in EJNMMI radiopharmacy and chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Kanchan KushwahaRadiation Medicine Centre, Bhabha Atomic Research Centre, Parel, Mumbai, India.
Kavindra PathakTechnical Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Tejinder P SabharwalTechnical Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Sunil KambleTechnical Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Arpit MitraRadiopharmaceuticals Laboratory, Board of Radiation and Isotope Technology, Navi Mumbai, India.
Sudeep SahuRadiation Medicine Centre, Bhabha Atomic Research Centre, Parel, Mumbai, India.
Pravind MalethaRadiation Medicine Centre, Bhabha Atomic Research Centre, Parel, Mumbai, India.
Nand Kishore PrasadTechnical Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Manish KumarTechnical Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Sharmila BanerjeeRadiation Medicine Centre, Bhabha Atomic Research Centre, Parel, Mumbai, India. banerjeesharmila2207@gmail.com.ORCID http://orcid.org/0000-0002-6094-1035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMolecular imaging enables the non-invasive visualization of physiological processes at the cellular and molecular levels and is central to diagnostic nuclear medicine. Among clinically important theranostic radionuclides,

resultsTo enhance the capability of the two-decade old commercial medical cyclotron (PETtrace 800) at the Radiation Medicine Centre (RMC), originally configured only for liquid and gaseous targets, an indigenously designed and fabricated solid target irradiation assembly was developed and integrated into the Medical Cyclotron Facility (MCF). This work demonstrates the successful routine production of pharmaceutical-grade

conclusionThis development significantly broadens the functional scope of the existing cyclotron infrastructure and establishes a dependable local production pathway for clinically important theranostic radionuclides.

Indexed as

111in64CuMedical cyclotronRadioisotope productionSolid target

Identifiers

PMID42236634
PMCPMC13451174

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LicenceCC BY-NC-ND
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