Evidence map›Paper›PMID 42236618›Full record

ReviewDiscover oncology2026

A comprehensive analysis and visualization of immune-related adverse events in lung cancer immunotherapy a bibliometric study.

Xiongjie Li, Fengyue Zhang, Xuan Xu

Abstract readReview
In one paragraph

Review in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiongjie Li *Cardiothoracic Thyroid & Breast Surgery Department, Hubei Jianghan Oilfield General Hospital, No. T32, An Kang Road, Guanghua Subdistrict, Qianjiang, 433100, Hubei, China. surobert518@163.com.
Fengyue Zhang *Gastroenterology Department, Hubei Jianghan Oilfield General Hospital, Qianjiang, 433100, Hubei, China.
Xuan XuCardiothoracic Thyroid & Breast Surgery Department, Hubei Jianghan Oilfield General Hospital, No. T32, An Kang Road, Guanghua Subdistrict, Qianjiang, 433100, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune-related adverse events (irAEs) significantly impact the therapeutic efficacy of immune checkpoint inhibitors (ICIs) in lung cancer. However, a comprehensive understanding of the global research landscape and its evolution regarding irAEs is still lacking.

methodsWe conducted a bibliometric analysis of 6787 publications from the Web of Science Core Collection (2015-2024) via CiteSpace and the R-bibliometrix package. The analyses included cocitation, coauthorship, and keyword burst detection to map collaborative networks, knowledge structure, and research trends.

resultsResearch output demonstrated a remarkable compound annual growth rate of 30.4%. INSERM (France) and US institutions appeared as central hubs in collaborative networks, whereas China-despite its high publication volume-showed more limited international integration, suggesting a productivity‑influence mismatch. The knowledge base comprises three clusters: clinical evidence, translational research, and fundamental immunology. Research themes evolved from initial tumor-agnostic safety reports to a focus on organ-specific irAEs and precision toxicology.

conclusionThis study delineates the rapidly evolving landscape of irAE research in lung cancer immunotherapy, highlighting key collaborative patterns, knowledge structures, and thematic shifts. The findings provide a foundational perspective for guiding future research directions.

Indexed as

Bibliometric analysisImmune-related adverse eventsImmunotherapyLung cancerResearch trends

Identifiers

PMID42236618
PMCPMC13469052

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.