ArticleAnalytical and bioanalytical chemistry2026
The compound-independent calibration of alkyl organophosphorus flame retardants in rice using GC-ICP-MS.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Organophosphorus flame retardants (OPFRs) are widespread environmental contaminants with bioaccumulative potential and associated human health risks. The lack of commercial reference standards for many OPFRs limits the accuracy of their quantification. In this study, a compound-independent calibration (CIC) method using gas chromatography-inductively coupled plasma mass spectrometry (GC-ICP-MS) was developed for the simultaneous quantification of seven alkyl OPFRs, with tripropyl phosphate (TnPP) as a single universal calibrant. Key parameters were optimized: a DB-5MS column (15 m × 0.25 mm × 0.10 μm) with pulsed splitless injection (70 psi, 280 °C), and ICP-MS settings including an RF power of 1600 W, sampling depth of 7.5 mm, dilution gas flow rate of 0.5 mL/min, and octopole voltage of - 5 V. The method exhibited excellent linearity (R
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