Evidence map›Paper›PMID 42236526›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Employment trends in schizophrenia and bipolar disorder in Spain: a nationwide register-based study (2018-2023).

Vicent Llorca-Bofí, Gerard Anmella, Daniel Guinart, Catalina Paredes-Coronel, Diego Hidalgo-Mazzei, Eduard Vieta, Miquel Bioque

Abstract read
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Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

7 authors.

Vicent Llorca-BofíBarcelona Clínic Schizophrenia Unit (BCSU), Hospital Clínic de Barcelona, Neuroscience Institute, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Catalonia, Spain. vicentllorcabofi@gmail.com.
Gerard AnmellaDepartment of Medicine, School of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), Barcelona, Catalonia, Spain.
Daniel GuinartBiomedical Research Networking Centre Consortium on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Catalina Paredes-CoronelClinical and Organizational Innovations Unit, Quirónsalud 4-H Network, Madrid, Spain.
Diego Hidalgo-MazzeiDepartment of Medicine, School of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), Barcelona, Catalonia, Spain.
Eduard VietaDepartment of Medicine, School of Medicine and Health Sciences, Institute of Neurosciences (UBNeuro), University of Barcelona (UB), Barcelona, Catalonia, Spain.
Miquel BioqueBarcelona Clínic Schizophrenia Unit (BCSU), Hospital Clínic de Barcelona, Neuroscience Institute, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Catalonia, Spain. mbioque@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmployment is a key determinant of recovery in severe mental illness, yet longitudinal evidence from Southern Europe is limited. We aimed to examine national trends in employment status among individuals with schizophrenia and bipolar disorder in Spain between 2018 and 2023.

methodsWe conducted a register-based trend study using the Spanish Primary Care Clinical Database (BDCAP), including adults aged 20-64 years with schizophrenia (n = 139,594), bipolar disorder (n = 148,968), or other diagnoses (n = 25,953,622). Employment status was classified as employed, unemployed, economically inactive, disability pensions, or other statuses. Trends were analysed with Joinpoint regression, reporting Average Annual Percent Change (AAPC) with 95% CIs.

resultsIn 2023, 15.2% of people with schizophrenia and 38.3% with bipolar disorder were employed, versus 62.5% with other conditions. Disability pensions were received by 49.3% and 26.5%, compared with 6.3% in other diagnoses. Between 2018 and 2023, employment rose modestly in schizophrenia (AAPC =  + 2.2; 95% CI 0.8-3.6; p < 0.001) and bipolar disorder (+ 2.4; 95% CI 1.6-3.2; p < 0.001), while disability pensions declined (-5.5; 95% CI - 8.9 to - 2.1; p = 0.003; and - 7.2; 95% CI - 9.4 to - 5.1; p < 0.001). The "other statuses" category grew sharply (schizophrenia + 52.8; bipolar disorder + 35.4; both p < 0.001). Sex-stratified analyses showed parallel trends, except for economic inactivity, which declined more steeply among women (Δ trend =  + 3.1, p = 0.029; + 2.7, p = 0.031; + 3.2, p = 0.008).

conclusionsEmployment outcomes remain poor for people with schizophrenia and bipolar disorder in Spain. Most improvements likely reflect administrative changes rather than genuine integration into work.

Indexed as

Bipolar DisorderEmploymentRegistriesSchizophreniaAdultFemaleHumansMaleMiddle AgedSpainYoung AdultBipolar disorderEmploymentLongitudinal trendsPopulation-based dataSchizophreniaSpain

Identifiers

PMID42236526
PMCPMC13525965

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