ArticleScientific data2026
Pan-genome based on chromosome sequences of wild and cultivated Agaricus bisporus.
Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Agaricus bisporus, one of the most widely cultivated mushrooms around the world, plays an important role in economy and agriculture. In this study, by employing long-reads generated by PacBio and Nanopore sequencing, we assembled six novel high-quality genomes (of which three are telomere-to-telomere assemblies) with sizes 29.6 ~ 30.8 Mb and N50 lengths of 2.5 ~ 2.6 Mb. Combined with public genome data of nine strains, we successfully established a pan-genome of A. bisporus, comprising a total of 14,626 clusters of protein coding genes, of which 50.70%, 7.45%, 24.74% and 17.01% are defined as core, soft core, dispensable, and private clusters, respectively. A total of 5,646 non- redundant structural variants (SVs) were identified among wild and cultivated strains and the genes associated with SV were mapped. This work provides valuable whole-genome sequences and genomic resources across wild and cultivated strains of the most widely cultivated mushroom species for functional analyses of genomes.
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