Evidence map›Paper›PMID 42236474›Full record

ReviewNPJ vaccines2026

Chitosan nanoparticles for mucosal and needle-free vaccination.

Changchun Chen, Cheng Zhang, Shanyuan Zhu, Shinuo Cao

Abstract readReview
In one paragraph

Review in NPJ vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Changchun Chen *Jiangsu Agri-animal Husbandry Vocational College, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, China.
Cheng Zhang *Jiangsu Agri-animal Husbandry Vocational College, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, China.
Shanyuan ZhuJiangsu Agri-animal Husbandry Vocational College, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, China. JSNM_ZSY@126.com.
Shinuo CaoJiangsu Agri-animal Husbandry Vocational College, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, China. shinuo_cao@163.com.

Funding

Jiangsu Zhongmu Beikang Scientific Research Project 2024BKYF02the project of Jiangsu Agri-animal Husbandry Vocational College NSF2026ZR04the Taizhou Science and Technology Support Project (Agriculture) TN202415
6 · The paper itself

Abstract

Chitosan nanoparticles are emerging as versatile vaccine carriers that enhance antigen stability, improve mucosal delivery, and strengthen immune activation. This review synthesizes advances in their biological functions, chemical engineering, fabrication, and performance across inactivated, subunit, and nucleic acid vaccines. It defines structure function principles that guide rational design for thermostable and effective immunization, highlighting the promise of needle free mucosal vaccination for scalable use across diverse settings.

Identifiers

PMID42236474
PMCPMC13542248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.