Evidence map›Paper›PMID 42236383›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2026

Interpersonal Predictors of Grief Among Caregivers of Persons With Dementia.

Lucas Owens, Holly G Prigerson, Francesca B Falzarano, Paul K Maciejewski

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucas OwensCollege of Medicine (LO), California Northstate University (CNU), Elk Grove, CA.
Holly G PrigersonDepartment of Radiology, Cornell Center for Research on End-of-Life Care (HGP, PKM), Weill Cornell Medicine, New York, NY. Electronic address: hgp2001@med.cornell.edu.
Francesca B FalzaranoLeonard Davis School of Gerontology (FBF), University of Southern California, Los Angeles, CA.
Paul K MaciejewskiDepartment of Radiology, Cornell Center for Research on End-of-Life Care (HGP, PKM), Weill Cornell Medicine, New York, NY.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
The Weill Cornell Medicine Research Training Program in Behavioral GeriatricsT32AG049666 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI SARA J CZAJA, Manney Carrington Reid · 2016 to 2026
$3.2M
A Multisite Randomized Controlled Trial of EMPOWER for Family Surrogates of Critically Ill PatientsR01NR019831 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI LICHTENTHAL, WENDY G., PRIGERSON, HOLLY GWEN · 2022 to 2025
$3.2M
Bridge to Better End-of-Life Care for Patients with Cancer: Connecting Healthcare Chaplains with Spiritual Care Providers in Faith CommunitiesR01NR021159 · NINR · WEILL MEDICAL COLL OF CORNELL UNIV · PI ASTROW, ALAN BENNETT, MACIEJEWSKI, PAUL K · 2024 to 2025
$1.7M
The Caregiver Resource Room: Enhancing Support for Caregivers of Alzheimer's Disease and Related Dementias (ADRD)R00AG073509 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FALZARANO, FRANCESCA · 2023 to 2025
$724k
Pilot Trial of a "Divine Intervention" to Improve End-of-Life Cancer Care for Black PatientsR21MD017652 · NIMHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2023 to 2025
$495k
The Living Memory Home: Reducing Grief and Improving Relationships between Home-based Patients with ADRD and Their Family CaregiversR21AG077144 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI FALZARANO, FRANCESCA, PRIGERSON, HOLLY GWEN · 2023 to 2024
$481k
Automated Detection of Suicide Attempt Risk among Bereaved IndividualsR21MH121886 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MACIEJEWSKI, PAUL K, PRIGERSON, HOLLY GWEN · 2020 to 2021
$454k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCI NIH HHS R35 CA197730NIA NIH HHS R00 AG073509NIA NIH HHS R21 AG077144NIA NIH HHS T32 AG049666NIMHD NIH HHS R21 MD017652NIMH NIH HHS R21 MH121886NINR NIH HHS R01 NR019831NINR NIH HHS R01 NR021159
6 · The paper itself

Abstract

objectiveFamily caregivers of persons with dementia experience grief as the care recipients' dementia advances. Here, we explore how various interpersonal factors hypothesized to relate to prolonged grief disorder (PGD) (e.g., perceived burdensomeness, thwarted belongingness) and our micro-social theory of grief (e.g., relational deprivation, self-esteem-related social support) relate to caregiver dementia-related grief. DESIGN, SETTING, AND

participantsBaseline caregiver data (N = 69) from an National Institute on Aging funded randomized pilot trial evaluating a digital reminiscence platform for dementia family caregiver-care‑recipient dyads were analyzed. Apparent (unadjusted), independent, and most significant associations between 12 interpersonal constructs and caregiver dementia-related grief were assessed using ordinary, multiple, and stepwise linear regression, respectively. MEASURES: Dementia‑specific grief was measured using a 10‑item adaptation of the Prolonged Grief-12. Interpersonal constructs were measured using the Interpersonal Support Evaluation List, the Interpersonal Needs Questionnaire, and the Relational Deprivation Scale.

resultsIn ordinary regression models, 10 interpersonal constructs were apparently associated with caregiver grief. In a multiple regression model, only perceived burdensomeness (β = 0.30; t = 2.25, df = 56, p = 0.029) and relational deprivation (β = 0.21; t = 2.05, df = 56, p = 0.045) were independently associated with caregiver grief. In a stepwise regression model, self-esteem-related social support (β = -0.41; t = -3.53, df = 65, p = 0.001) was associated with lesser, and perceived burdensomeness (β = 0.30; t = 2.50, df = 65, p = 0.015) and relational deprivation (β = 0.25; t = 2.84, df = 65, p = 0.006) were associated with greater caregiver dementia-related grief.

conclusionPerceived burdensomeness, a risk for suicidal ideation, and relational deprivation and self-esteem-related social support, theoretically aligned with our micro-social theory of grief, were most significantly predictive of caregiver dementia-related grief. Interventions addressing grief among dementia caregivers should target these influential interpersonal vulnerabilities.

Indexed as

CaregiversDementiaGriefInterpersonal RelationsProlonged Grief DisorderSocial SupportAgedAged, 80 and overFemaleHumansMaleMiddle AgedPilot ProjectsSelf ConceptForme fruste keratoconusmachine learningoptical coherence tomographyradiomics

Identifiers

PMID42236383
PMCPMC13267865

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.