Evidence map›Paper›PMID 42236205›Full record

ArticleThe Journal of veterinary medical science2026

Histopathology of skeletal dysplasia in a Japanese Black calf with marked epiphyseal enlargement.

Tomoki Nakamura, Ami Iwata, Mitsutaka Ikezawa, Ryouko Tsuji, Yuji Takamura, Kouhei Inagaki, Takashi Masuda, Sohta Hishikawa, Yuji Sunden

Abstract readCase Reports
In one paragraph

Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomoki NakamuraAichi Prefectural Chuo Livestock Hygiene Service Center, Aichi, Japan.
Ami IwataAichi Prefectural Chuo Livestock Hygiene Service Center, Aichi, Japan.
Mitsutaka IkezawaDivision of Transboundary Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), Tokyo, Japan.
Ryouko TsujiAichi Prefectural Chuo Livestock Hygiene Service Center, Aichi, Japan.
Yuji TakamuraLivestock Industry Division, Bureau of Agriculture and Fisheries, Aichi Prefectural Government, Aichi, Japan.
Kouhei InagakiAichi Prefectural Seibu Livestock Hygiene Service Center, Aichi, Japan.
Takashi MasudaAichi Prefectural Chuo Livestock Hygiene Service Center, Aichi, Japan.
Sohta HishikawaLaboratory of Veterinary Pathology, Joint Graduate School of Veterinary Sciences, Tottori University, Tottori, Japan.
Yuji SundenLaboratory of Veterinary Pathology, Joint Graduate School of Veterinary Sciences, Tottori University, Tottori, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 16-day-old male Japanese Black calf affected by skeletal dysplasia, a recessive genetic disorder characterized by marked enlargement of the limb joints due to epiphyseal enlargement. Histological examination revealed chondrocyte proliferation in both the humeral and femoral growth plates, with disorganized chondrocyte alignment and fewer bone trabeculae observed in the humerus. These findings suggest that the morphological changes of chondrocytes may be imbalanced during endochondral ossification at the growth plate. Joint enlargement was evident in the epiphyseal region at birth, despite the absence of articular chondrocyte hyperplasia. Although the details of the pathological mechanism remain unclear, cartilaginous epiphysis overgrowth during embryonic development or secondary ossification center expansion during endochondral ossification may cause the joint enlargement observed in this genetic disorder.

Indexed as

Bone Diseases, DevelopmentalCattle DiseasesGrowth PlateAnimalsCattleChondrocytesEpiphysesMaleepiphyseal enlargementgrowth plateJapanese Black calfskeletal dysplasia

Identifiers

PMID42236205
PMCPMC13500382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.