Evidence map›Paper›PMID 42235616›Full record

ArticleThe Journal of arthroplasty2026

Is Fretting Corrosion at the Modular Junction of Revision Total Knee Arthroplasty Actually a Problem?

Deborah J Hall, John Wong, Jennifer L Wright, Julia P Hochstatter, Robert A Burnett, Amy Miller, Brett R Levine, Robin Pourzal, E Bailey Terhune

Abstract read
In one paragraph

Article in The Journal of arthroplasty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deborah J HallDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
John WongDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Jennifer L WrightDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Julia P HochstatterDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Robert A BurnettDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Amy MillerDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Brett R LevineDepartment of Orthopedic Surgery, MedStar Georgetown University Hospital, Washington, District of Columbia.
Robin PourzalDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
E Bailey TerhuneDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.

Funding

Preclinical Assessment Tools for Preventing Fretting-Corrosion within Modular Junctions of Total Joint ReplacementR01AR084468 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI Hannah Jean Lundberg, Mathew Thoppil Mathew · 2025 to 2026
$1.1M
Corrosion Induced Hip Implant Failure: Synergistic Interactions of Patient, Material, Design, and Surgical FactorsR56AR070181 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI LUNDBERG, HANNAH JEAN, MATHEW, MATHEW THOPPIL · 2022 to 2022
$677k
NIAMS NIH HHS R01 AR084468NIAMS NIH HHS R56 AR070181
6 · The paper itself

Abstract

backgroundCorrosion at modular junctions in total knee arthroplasty (TKA) implants is recognized, but its clinical relevance remains unclear. This study evaluated corrosion at modular stem-bore junctions and examined whether severity correlated with radiographic evidence of adverse local tissue reactions or osteolysis.

methodsWe evaluated 196 retrieved modular stem and bore components from 98 revision TKA patients, including taper (n = 73) and threaded (n = 25) designs. The median time in situ was 24 months for taper and 15 months for threaded junctions (P = 0.052). Periprosthetic joint infection and aseptic loosening were the most common indications for component explantation. Fretting corrosion at the modular junction was graded using a modified Goldberg Score (mGS) and quantified using an optical coordinate measuring machine. Radiographs were evaluated. Statistical analyses included Mann-Whitney U-, Chi-Square, and Spearman's correlation tests.

resultsTaper junctions demonstrated greater corrosion than threaded designs (P < 0.001). The median mGS for modular tapers was 4 for femoral components, 3 for femoral stems, and two for both tibial components and stems. Threaded junctions showed minimal damage across all interfaces with a median score of 1. Damage patterns included fretting wear, corrosion features, and dark deposits. Among cobalt-chromium (CoCr) femoral bore tapers with mGS of 4, median material loss was 0.56 mm

conclusionsIn this study of modular TKA components, taper junctions exhibited significantly more corrosion than threaded junctions. However, corrosion severity was not associated with radiographic findings or etiology of failure. Corrosion products differed from those typically observed in THA, suggesting a distinct mechanism. Further research is required to clarify potential clinical implications.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisProsthesis FailureAgedAged, 80 and overCorrosionFemaleHumansMaleMiddle AgedProsthesis DesignRadiographyReoperationfretting corrosionmodular junctionrevision knee arthroplastytaper damagetotal knee arthroplasty

Identifiers

PMID42235616
PMCPMC13333113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.