Evidence map›Paper›PMID 42235486›Full record

ArticleNeuron2026

The rewarding crunch: A brainstem circuit links incisor mechanosensation to motivated gnawing.

Jun Takatoh, Fan Wang

Abstract readComment
In one paragraph

Article in Neuron, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jun TakatohDepartment of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, USA. Electronic address: jun.takato@stonybrook.edu.
Fan WangMcGovern Institute for Brain Research, MIT, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA; Yang Tan Collective, MIT, Cambridge, MA 02139, USA. Electronic address: fan_wang@mit.edu.

Funding

Top-down and bottom-up signals for flexible orofacial behaviorsU19NS137920 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael Nicholas Economo · 2024 to 2026
$15.9M
The brainstem vocal control circuitsR01DC021970 · NIDCD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Fan Wang, Shenqin Yao · 2024 to 2026
$1.7M
NIDCD NIH HHS R01 DC021970NINDS NIH HHS U19 NS137920
6 · The paper itself

Abstract

Gnawing maintains ever-growing rodent incisors, yet the underlying circuit has remained unknown. In this issue of Neuron, Su et al.

Indexed as

Brain StemMechanoreceptorsMotivationRewardAnimalsMotor Neurons

Identifiers

PMID42235486
PMCPMC13410560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.