Evidence map›Paper›PMID 42234651›Full record

ArticlePloS one2026

Examining the uptake, retention, and effectiveness of a national online type 2 diabetes self-management intervention in England (Healthy Living): A retrospective cohort study.

Salwa S Zghebi, Sarah Cotterill, Antonia Marsden, Luke Paterson, Rachel A Elliott, Brian McMillan, Martin K Rutter, Evangelos Kontopantelis

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Salwa S ZghebiCentre for Primary Care and Health Services Research, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-7978-1094
Sarah CotterillCentre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Antonia MarsdenCentre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Luke PatersonManchester Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Rachel A ElliottManchester Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Brian McMillanCentre for Primary Care and Health Services Research, Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-0683-3877
Martin K RutterDiabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK.
Evangelos KontopantelisDivision of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0001-6450-5815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of type 2 diabetes (T2DM) is increasing rapidly in the UK and worldwide and is linked to adverse outcomes including premature death. Previous studies have shown that developing self-management skills in this population can lead to health improvements. The National Health Service in England has implemented Healthy Living (HL), an online Diabetes Self-Management Education and Support (DSMES) intervention, offering information about T2DM and help with adopting healthy behaviours.

aimsTo examine the uptake and retention of people living with T2DM registered with Healthy Living and how its use is associated with changes in 1-year clinical outcomes (effectiveness) compared with people with T2DM who did not register (controls).

methodsAnonymised linked patient-level Healthy Living and National Diabetes Audit (NDA) data were used to identify adults with T2DM in England. Multivariable logistic regression models identified predictors of participation in Healthy Living (uptake). Using 1-to-5 case-control propensity score matching (on age, sex, baseline HbA1c, body mass index (BMI), blood pressure (BP), cholesterol, ethnicity, deprivation) and multivariable linear and logistic models, we examined how Healthy Living use was related to 1-year HbA1c, BMI, BP, new insulin use, and completion of eight care processes recommended for people with diabetes (effectiveness). Several sensitivity and sub-group analyses were conducted to assess the robustness of the findings.

resultsA total of 21,820 people with T2DM activated a Healthy Living account. Compared with non-participants, account activators (cases) were more likely to be female (OR: 1.91; 95%CI: 1.85, 1.96), less likely to be Asian (OR: 0.35; 95% CI: 0.33, 0.37) or Black (OR: 0.56; 95% CI: 0.52, 0.60) compared with white people. Assessing effectiveness, 4,940 Healthy Living cases were matched to 24,685 NDA controls. Compared with controls, at 1-year, Healthy Living cases had lower HbA1c (by -1.3 mmol/mol (95% CI: -1.7, -0.8) or -0.1% (95% CI: -0.2, -0.1)); BMI (-0.2 kg/m2; 95% CI: -0.3, -0.1), systolic BP (-1.2 mmHg; 95% CI: -1.6, -0.7), and diastolic BP (-0.6 mmHg; 95% CI: -0.9, -0.3); higher odds of completing care processes (OR: 1.6; 95% CI: 1.5, 1.8), but non-significant for insulin use (OR: 1.0; 95% CI: 0.8, 1.2). The results of the sensitivity and sub-group analyses were consistent with the main findings.

conclusionsPeople who activated a Healthy Living account experienced, on average, moderate health benefits compared with non-participants. These benefits would be expected to reduce risks for diabetes-related complications at a population level.

Indexed as

Diabetes Mellitus, Type 2Self-ManagementAdultAgedCase-Control StudiesEnglandFemaleGlycated HemoglobinHumansMaleMiddle AgedRetrospective StudiesSelf CareGlycated Hemoglobin

Identifiers

PMID42234651
PMCPMC13232854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.