Evidence map›Paper›PMID 42234558›Full record

ArticleCell reports2026

PDGF signaling regulates the adipocyte-to-fibroblast transition in wound healing.

Longbiao Yao, Sunhye Jeong, Jacob Bass, Hae Ryong Kwon, Lorin E Olson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Longbiao YaoCardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73014, USA.
Sunhye JeongCardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73014, USA.
Jacob BassFlow Cytometry Core Facility, Oklahoma Medical Research Foundation, Oklahoma City, OK 73014, USA.
Hae Ryong KwonCardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73014, USA.
Lorin E OlsonCardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73014, USA. Electronic address: lorin-olson@omrf.org.

Funding

Viral sensor IFIH1 promotes SLE through an altered interferon programP20GM139763 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI Jon Iker Etchegaray · 2021 to 2026
$20.3M
PDGFRB Signaling in Progressive Skin DiseaseR01AR080896 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI LORIN E OLSON · 2023 to 2026
$2.1M
Deciphering the myofibroblast life cycle in skin wound healingF32AR083823 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI Sunhye Jeong · 2024 to 2026
$243k
NIAMS NIH HHS F32 AR083823NIAMS NIH HHS R01 AR080896NIGMS NIH HHS P20 GM139763
6 · The paper itself

Abstract

Adipocytes are plastic cells with the ability to transition into fibroblast-like cells during tissue repair or physiological remodeling. It is unclear how such transitions are regulated and whether they exemplify cell plasticity or merely a transient suppression of adipocyte features. Fibroblasts express platelet-derived growth factor receptors (Pdgfra and Pdgfrb), while adipocytes express adiponectin (Adipoq). Here, we use two-step lineage tracing to label Pdgfra

Indexed as

AdipocytesFibroblastsPlatelet-Derived Growth FactorSignal TransductionWound HealingAdiponectinAnimalsCell ProliferationMiceReceptor, Platelet-Derived Growth Factor alphaReceptor, Platelet-Derived Growth Factor betaAdiponectinPlatelet-Derived Growth FactorReceptor, Platelet-Derived Growth Factor alphaReceptor, Platelet-Derived Growth Factor betaadipocyteCP: cell biologyCP: developmental biologydedifferentiationfibroblasthair cyclelactationlineage tracingPDGFplasticitytransdifferentiationwound healing

Identifiers

PMID42234558
PMCPMC13398178

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.