Evidence map›Paper›PMID 42234535›Full record

ArticleInfection and immunity2026

Protective efficacy of mutant strains of

Venkatesh Kumaresan, Trever C Smith, Miranda Lumbreras, Taylor MacMackin Ingle, Nathan Kilgore, Jolie F Starling-Lin, Elizabeth J Horn, J Seshu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Venkatesh KumaresanSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0000-0003-1950-6231
Trever C SmithSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Miranda LumbrerasSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Taylor MacMackin IngleSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Nathan KilgoreSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Jolie F Starling-LinSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0000-0003-2101-122X
Elizabeth J HornBay Area Lyme Foundation, Portola Valley, California, USA.ORCID 0000-0001-5928-9652
J SeshuSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-4471-2435

Funding

Efficacy of novel reservoir-host targeted bait formulations against a tick-borne pathogenR01AI152233 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI SESHU, JANAKIRAM · 2021 to 2025
$1.9M
MMI-T32 Training Pre-doctoral Scientists in Molecular Microbiology and Immunology at UTSAT32AI184340 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI Astrid E Cardona, Jose L. Lopez-Ribot · 2024 to 2026
$463k
NIAID NIH HHS R01 AI152233NIAID NIH HHS T32 AI184340NIH HHS 5R01AI152233NIH HHS T32AI184340
6 · The paper itself

Abstract

Lyme disease (LD), caused by

Indexed as

Bacterial VaccinesBorrelia burgdorferiLyme DiseaseLyme Disease VaccinesAnimalsAntibodies, BacterialAntigens, BacterialBacterial ProteinsDisease Models, AnimalDisease ReservoirsFemaleHumansIxodesLipoproteinsMiceMice, Inbred C3HAntibodies, BacterialAntigens, BacterialBacterial ProteinsBacterial VaccinesLipoproteinsLyme Disease VaccinesBorrelia burgdorferilipoproteinsLyme diseasemouse models of infectionprotective immunity

Identifiers

PMID42234535
PMCPMC13367066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.