Evidence map›Paper›PMID 42234526›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Mutational analyses of an instability domain reveal its conserved role in the regulation of class-B ARF levels in

Zhaonan Ban, Michael J Prigge, Yinglin Zhu, Nicholas Morffy, Wesley R Neher, Andrew Muroyama, Lucia Strader, Mark Estelle

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhaonan BanDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0009-0004-5447-2027
Michael J PriggeDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-0671-2538
Yinglin ZhuDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.
Nicholas MorffyDepartment of Biology, Duke University, Durham, NC 27708.ORCID 0000-0003-3170-2032
Wesley R NeherDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-6810-0783
Andrew MuroyamaDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-0701-212X
Lucia StraderDepartment of Biology, Duke University, Durham, NC 27708.
Mark EstelleDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-2613-8652

Funding

NIGMS administrative equipment supplement for R35 GM136338-02R35GM136338 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Lucia Strader · 2020 to 2026
$3.2M
Novel auxin signaling components and pathways.R35GM141892 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESTELLE, MARK A · 2021 to 2025
$1.8M
Polarity mechanisms driving complex morphogenesisR35GM150466 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D Muroyama · 2023 to 2026
$1.6M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM136338HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM141892HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM150466.NIGMS NIH HHS R35 GM136338NIGMS NIH HHS R35 GM141892NIGMS NIH HHS R35 GM150466NIH HHS S10 OD026929
6 · The paper itself

Abstract

The plant hormone auxin is a central regulator of plant growth and development. The canonical nuclear auxin signaling pathway acts through the regulation of gene transcription, and the protein levels of core component AUXIN RESPONSE FACTORS (ARFs) are key to this regulation. Here, we investigate the physiological role of a conserved instability (INS) domain in two class-B ARFs, ARF2 and ARF3, in

Indexed as

ArabidopsisArabidopsis ProteinsTranscription FactorsGene Expression Regulation, PlantIndoleacetic AcidsMutationPlant RootsPlants, Genetically ModifiedProtein DomainsProtein StabilityRepressor ProteinsSignal TransductionArabidopsis ProteinsARF2 protein, ArabidopsisIndoleacetic AcidsRepressor ProteinsTranscription FactorsARFauxinplant development

Identifiers

PMID42234526
PMCPMC13250565

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.