Evidence map›Paper›PMID 42234515›Full record

ArticleInfection and immunity2026

Characterization of vesicle-associated exported immunodominant antigens of the human pathogen

Pallavi Singh, Anasuya C Pal, Jae-Yeon Choi, Meenal Chand, Pratap Vydyam, Geeta Kumari, Choukri Ben Mamoun

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pallavi SinghSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-2318-5960
Anasuya C PalSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-0068-8912
Jae-Yeon ChoiSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-9853-0987
Meenal ChandSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Pratap VydyamSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-4944-6006
Geeta KumariSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Choukri Ben MamounSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-5028-1400

Funding

Fosinopril analogs for the treatment of human babesiosisR01AI153100 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI · 2021 to 2025
$3.6M
Hit-to-Lead Development of the Kalihinol Scaffold for Malaria TreatmentR01AI138139 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BEN MAMOUN, CHOUKRI, LE ROCH, KARINE GAELLE · 2018 to 2022
$3.6M
Development of endochin-like quinolones for babesiosis therapyR01AI123321 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI · 2017 to 2020
$2.7M
Antigen Discovery and Vaccine Development for Human Babesia ParasitesR01AI152220 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI · 2020 to 2024
$2.1M
An antigen-detection assay to diagnose Babesia microti infectionR44AI136118 · NIAID · L2 DIAGNOSTICS, LLC · PI LEDIZET, MICHEL · 2020 to 2022
$2.1M
Parasite-Derived Vesicles in Babesia virulence and Vaccine DevelopmentR56AI177660 · NIAID · YALE UNIVERSITY · PI BEN MAMOUN, CHOUKRI, KASHANCHI, FATAH · 2024 to 2024
$874k
An antigen-detection assay to diagnose Babesia microti infectionR43AI136118 · NIAID · L2 DIAGNOSTICS, LLC · PI LEDIZET, MICHEL · 2018 to 2018
$300k
NIAID NIH HHS R01 AI123321NIAID NIH HHS R01 AI138139NIAID NIH HHS R01 AI152220NIAID NIH HHS R01 AI153100NIAID NIH HHS R43 AI136118NIAID NIH HHS R44 AI136118NIAID NIH HHS R56 AI177660NIH HHS AI123321NIH HHS AI136118NIH HHS AI138139NIH HHS AI152220NIH HHS AI153100
6 · The paper itself

Abstract

Human babesiosis is an emerging disease caused by intraerythrocytic

Indexed as

Antigens, ProtozoanBabesiaBabesiosisImmunodominant EpitopesAnimalsErythrocytesHumansMiceProtozoan ProteinsAntigens, ProtozoanImmunodominant EpitopesProtozoan ProteinsApicomplexaBabesiaB. duncani-derived vesicles (BDVs)human babesiosisparasitevesicles

Identifiers

PMID42234515
PMCPMC13367061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.