Evidence map›Paper›PMID 42234478›Full record

ArticleeLife2026

CO

Valentin Mihai Dospinescu, Alexander Mascarenhas, Jack Butler, Sarbjit Nijjar, Kyara de Oliveira Taborda, Sean Connors, Lumei Huang, Nicholas Dale

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Connexin50 hemichannels are opened by COFrontiers in physiology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentin Mihai Dospinescu *School of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0002-5988-8409
Alexander Mascarenhas *School of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0009-0008-6845-4726
Jack ButlerSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-2985-6841
Sarbjit NijjarSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Kyara de Oliveira TabordaSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Sean ConnorsSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Lumei HuangSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-9479-2181
Nicholas DaleSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-2196-2949

Funding

Biotechnology and Biological Sciences Research Council BB/T00746X/1Biotechnology and Biological Sciences Research Council BB/T013346/1Medical Research Council MR/N014294/1
6 · The paper itself

Abstract

Sequence and structure comparisons between alpha and beta connexins, Cx43 and Cx26, revealed that Cx43 has a motif, the carbamylation motif, that confers CO

Indexed as

Carbon DioxideConnexin 43Ion Channel GatingAdenosine TriphosphateAnimalsConnexin 26HippocampusMicePatch-Clamp TechniquesSynaptic TransmissionAdenosine TriphosphateCarbon DioxideConnexin 26Connexin 43carbamylationcell biologyconnexinshemichannelmouseneuroscience

Identifiers

PMID42234478
PMCPMC13233067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.