ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
15 authors.
Funding
Abstract
Non-anastomotic stricture (NAS), a severe liver transplantation (LT) complication, is pathologically defined by biliary fibrosis, with unclear mechanisms and limited pharmacological therapeutic strategies. Single-cell RNA sequencing was performed on the bile duct tissues of NAS patients, ongoing (fibrosis persistent group) or succeeding (fibrosis remission group) in endoscopic treatment. Integrated analysis indicated that biliary epithelial-mesenchymal transition (EMT) and fibrosis were reduced in the fibrosis remission group than in the fibrosis persistent group. VIM
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Registered trials
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