Evidence map›Paper›PMID 42234206›Full record

ArticleJournal of cardiovascular translational research2026

Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.

Xiaoping Ning, Hongjie Xu, Quangong Zhao, Jiajun Pan, Xiaohong Liu, Jingyi Cao, Qin Li, Sufan Ding, Chao Ye, Keng Zhong and 5 more

Abstract read
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In one paragraph

Article in Journal of cardiovascular translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Xiaoping Ning *Department of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Hongjie Xu *National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, 210002, China.
Quangong Zhao *Department of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Jiajun PanDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Xiaohong LiuDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Jingyi CaoDepartment of Cardiovascular Surgery, Shanghai General Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Qin LiDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Sufan DingDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Chao YeDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Keng ZhongDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Shangyi YuDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Fanglin LuDepartment of Cardiovascular Surgery, Shanghai General Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Lin HanDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Zhiyun XuDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China. xuzhiyun_smmu@163.com.
Fan QiaoDepartment of Cardiovascular Surgery, Changhai hospital affiliated to the Naval Medical University, Shanghai, 200433, China. qiaofan_smmu@163.com.ORCID 0009-0005-1432-0544

Funding

Key Research and Development Program of the Ministry of Science and Technology of China 2022YFC2503404the National Natural Science Foundation of China No. 82070402the National Natural Science Foundation of China No. 82370380
6 · The paper itself

Abstract

We aimed to establish a rat TR model to further investigate the mechanisms of right heart remodeling and organ damage induced by TR. Intervention group rats (n = 6) underwent coronary stent system implantation via transjugular approach. The control group (n = 6) underwent the same procedure, except for coronary stent implantation. All rats survived at 8 weeks follow-up postoperatively. TR occurred immediately after the implantation of coronary stent in the intervention group. The right ventricular fractional area change (FAC) decreased by 33.9% compared with baseline from 0.59 ± 0.11% to 0.39 ± 0.10% (P = 0.005) and the tricuspid annular plane systolic excursion (TAPSE) decreased by 36.8% from 2.42 ± 0.31 mm to 1.53 ± 0.45 mm at 8 weeks (P < 0.001). This animal model would be suitable to further investigate the mechanisms of right ventricular remodeling and other organ damage associated with TR.

Indexed as

Cardiac CatheterizationHeart Valve Prosthesis ImplantationJugular VeinsStentsTricuspid ValveTricuspid Valve InsufficiencyAnimalsDisease Models, AnimalMaleRats, Sprague-DawleyTime FactorsVentricular Function, RightVentricular RemodelingRat modelRight ventricular remodelingTransjugularTricuspid regurgitation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.