ArticleWorld journal of urology2026
Radical cystectomy in octogenarians: a propensity score-matched analysis of short-term outcomes.
Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to compare the impact of biological versus chronological age on postoperative risk after radical cystectomy (RC) by evaluating whether age ≥ 80 years independently predicts short-term mortality, complications and readmission rates beyond physiological status and comorbidity burden.
methodsWe retrospectively analysed 879 patients undergoing open RC at a high-volume centre between 2015 and 2024. Propensity score matching (PSM; 1:1 nearest neighbor) was performed to balance octogenarians (80-89 years) and patients < 80 years for key covariates including ASA score, CCI score, BMI, renal function, preoperative albumin levels and urinary diversion. Primary endpoints were 30-day and 90-day mortality. Secondary endpoints included major complications (Clavien-Dindo ≥IIIb), 30- and 90-day readmission rates.
resultsAmong 879 patients, 114 (13%) were octogenarians. Primary analyses demonstrated a higher 30-day (6.1% vs. 1.4%; p = 0.003) and 90-day mortality (10.5% vs. 3.9%; p = 0.004) in octogenarians compared to patients < 80 years. After PSM (n = 194), mortality remained numerically higher in octogenarians (30-day: 6.2% vs. 2.1%; 90-day: 10.3% vs. 4.1%); however, these differences did not reach statistical significance (p = 0.28 and p = 0.165). Major complication and readmission rates were comparable between matched cohorts. In the multivariable regression analysis, age ≥ 80 years was not an independent predictor of any adverse outcome. Limitations include the retrospective design, single-centre setting and limited number of events after PSM.
conclusionWhen comorbidity burden and physiological fitness are comparable, octogenarians undergoing RC achieve short-term outcomes similar to those of younger patients. Chronological age alone should not preclude consideration of RC. Individualised risk assessment, treatment in experienced, high-volume centres and most likely, increasing adoption of robot-assisted RC are essential for safe surgical care for older RC candidates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.