ArticleAnalytical and bioanalytical chemistry2026
From bulk samples to single cells: measurement strategies in Raman-based antibiotic susceptibility testing.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Raman-spectroscopy based antibiotic susceptibility testing (AST) enables rapid phenotypic analysis of bacterial responses to antibiotics. However, many established approaches rely on bulk bacterial material, limiting their applicability to samples with low and variable cell numbers, such as urine, where washing or medium exchange is often impractical. We systematically compare three Raman-based measurement strategies differing in sample preparation and cellular presentation: (i) dried bulk measurements on CaF
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