Evidence map›Paper›PMID 42234030›Full record

ArticleTheoretical medicine and bioethics2026

The last low whispers revisited: a reply to Sulmasy on palliative sedation.

Harrison Lee

Abstract read
In one paragraph

Article in Theoretical medicine and bioethics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Harrison LeeUniversity of Mississippi, Oxford, USA. harrisonlee89@gmail.com.ORCID http://orcid.org/0009-0000-5583-094X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many ethicists who have opposed euthanasia have nonetheless approved of various practices which have been believed to hasten, or risk hastening, the death of terminally ill and suffering patients. For instance, they have approved of a practice which I shall call 'end-of-life sedation,' or 'EOL sedation.' This practice involves administering drugs with sedating effects to relieve suffering at the end of life. Some have believed that EOL sedation risks hastening death by suppressing respiration in certain cases. The main difference, according to these opponents of euthanasia, is that whereas euthanasia by definition involves an intention to kill, EOL sedation does not. At most, it is argued, EOL sedation foreseeably but unintentionally hastens, or risks hastening death as a byproduct of relieving the patient's suffering while they are still alive. As such, it has been argued that EOL sedation is supported by the rule of double effect (RDE). In his paper, "The last low whispers of our dead," Daniel P. Sulmasy raises objections to a specific form of EOL sedation called 'palliative sedation,' focusing especially on two variants of that practice which have been defended by Timothy Quill and colleagues. Palliative sedation involves intentionally sedating a patient as a means of relieving their suffering rather than foreseeably sedating them as a byproduct of targeting specific symptoms. Sulmasy argues that palliative sedation, so defined, is neither supported by RDE nor permissible. Here it is argued that Sulmasy's criticisms of this practice, and of the specific variants of it which he singles out for special criticism, are unsuccessful.

Indexed as

Hypnotics and SedativesPalliative CareProcedural SedationTerminal CareDouble Effect PrincipleEuthanasiaHumansRight to DieUnconsciousnessHypnotics and SedativesDaniel P. SulmasyDouble effectPalliative sedationTerminal sedationTimothy E. QuillValue of consciousness

Identifiers

PMID42234030
PMCPMC13263288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.