Evidence map›Paper›PMID 42234007›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Translation of a novel EphA2-targeted PET tracer from preclinical models to first-in-human studies in pancreatic cancer.

Xinyu Liu, Li Sun, Jialiang Lei, Liyan Bai, Haoyao Guo, Yichong Fang, Jianping Zhang, Chunjuan Jiang, Xiaoping Xu, Shaoli Song

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyu Liu *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Li Sun *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Jialiang LeiDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Liyan BaiDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Haoyao GuoDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Yichong FangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Jianping ZhangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China.
Chunjuan JiangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China. tsyxy2004@163.com.
Xiaoping XuDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China. xxp0012@ustc.edu.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, No. 270 Dong'an Road, Xuhui District, Shanghai, 200032, China. shaoli-song@163.com.ORCID http://orcid.org/0000-0003-2544-7522

Funding

Key Programme U23A20465National Natural Science Foundation of China 12275057National Natural Science Foundation of China 52403213National Natural Science Foundation of China 82272035Shanghai Oriental Talents Program Youth Project SSF828085Zhejiang Provincial Natural Science Foundation of China ZCLMS26C1001
6 · The paper itself

Abstract

purposeEphrin type-A receptor 2 (EphA2) is a promising target in pancreatic ductal adenocarcinoma (PDAC). However, the clinical potential of targeting EphA2 requires further imaging evaluation. This study developed and preliminarily evaluated a novel

methods

resultsThe three

conclusionA series of

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsPositron Emission Tomography Computed TomographyRadiopharmaceuticalsReceptor, EphA2AnimalsCell Line, TumorFemaleGallium RadioisotopesHumansMaleMiceMiddle AgedPilot ProjectsRadioactive TracersTissue DistributionEPHA2 protein, humanGallium RadioisotopesRadioactive TracersRadiopharmaceuticalsReceptor, EphA2EphA2 receptorPancreatic ductal adenocarcinomaPeptide radiopharmaceuticalsPET/CT imaging

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.