Evidence map›Paper›PMID 42233707›Full record

ArticleProceedings (Baylor University. Medical Center)2026

Venous thromboembolic events in traumatic brain injury. Does timing of prophylaxis matter? A single-center retrospective cohort study.

Nicholas Hernandez, Avery Christensen, Marissa Shumaker, Colby McClaugherty, Asad Danka, Michael P Hofkamp, Awais Z Vance

Abstract read
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas HernandezDepartment of Neurosurgery, Baylor College of Medicine, Temple, Texas, USA.ORCID 0009-0003-9026-5714
Avery ChristensenDepartment of Neurosurgery, Baylor College of Medicine, Temple, Texas, USA.
Marissa ShumakerDepartment of Neurosurgery, Baylor College of Medicine, Temple, Texas, USA.ORCID 0009-0005-5636-5089
Colby McClaughertyDepartment of Neurosurgery, Baylor College of Medicine, Temple, Texas, USA.ORCID 0009-0003-5397-532X
Asad DankaDepartment of Neurosurgery, Baylor College of Medicine, Temple, Texas, USA.ORCID 0009-0006-7792-8861
Michael P HofkampDepartment of Anesthesiology, Baylor Scott & White Medical Center - Temple, Temple, Texas, USA.ORCID 0000-0002-5749-2849
Awais Z VanceDepartment of Neurosurgery, Baylor Scott & White Medical Center - Temple, Temple, Texas, USA.ORCID 0000-0001-8815-3965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with traumatic brain injury (TBI) are at increased risk for venous thromboembolism (VTE) due to immobilization and a hypercoagulable state. The administration and optimal timing for chemoprophylaxis remain unclear because of concerns about safety and efficacy.

methodsWe conducted a retrospective review of adult patients admitted with TBI to a level I trauma center between January 2019 and May 2020. Patient demographics, Glasgow Coma Scale, mobility score, mechanism of injury, comorbidities, timing of chemoprophylaxis and physical therapy, VTE events, and intracranial hemorrhage complications were analyzed. Multivariate logistic regression was performed to identify predictors of VTE.

resultsAmong 405 patients, 161 received chemoprophylaxis. Eight patients experienced VTE. Receipt of prophylaxis in ≤48 hours was not associated with reduced VTE risk ( DISCUSSION: Higher admission mobility scores predict lower VTE risk in TBI. Early prophylaxis timing was not statistically associated with VTE. These findings underscore the need for prospective studies to determine safe and effective chemoprophylaxis strategies.

Indexed as

AnticoagulantsBrain Injuries, TraumaticVenous ThromboembolismAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTime FactorsAnticoagulantsChemoprophylaxisdeep vein thrombosisintracranial hemorrhagetraumatic brain injuryvenous thromboembolism

Identifiers

PMID42233707
PMCPMC13523933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.