Evidence map›Paper›PMID 42233500›Full record

ReviewAllergy2026

Leveraging Artificial Intelligence in Allergy, Asthma, and Immunology With Environmental Exposures.

Thinh H Nguyen, Cezmi A Akdis, Andrea Baccarelli, Sudipto Banerjee, Rohan Tan Bhowmik, Brent Coull, Marissa L Childs, Luigi Cao Pinna, Christopher D Golden, Thomas Hartung and 14 more

Abstract readReview
In one paragraph

Review in Allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Thinh H NguyenDivision of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6660-6556
Cezmi A AkdisSwiss Institute of Allergy and Asthma Research (SIAF), University Zurich, Davos, Switzerland.ORCID https://orcid.org/0000-0001-8020-019X
Andrea BaccarelliDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-3436-0640
Sudipto BanerjeeUCLA Fielding School of Public Health, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-2239-208X
Rohan Tan BhowmikStanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-3556-4370
Brent CoullDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-1808-4156
Marissa L ChildsDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-8597-2161
Luigi Cao PinnaSchool of Mathematics and Statistics, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0002-1152-258X
Christopher D GoldenDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2258-7493
Thomas HartungCenter for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-1359-7689
Benjamin Q HuynhDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-1372-7992
Abhinav KaushikDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-5682-0209
Oladimeji MudeleDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-7131-6334
Wanda PhipatanakulDepartment of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8639-0473
Chirag J PatelDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8756-8525
Bernardo Sousa PintoDepartment of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-1277-3401
John QuackenbushDepartment of Biostatistics & Computational Biology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2702-5879
Vanitha SampathDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-9639-5024
Jaime ToneySchool of Geographical and Earth Sciences, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0003-3182-6887
Meiliu WuSchool of Geographical and Earth Sciences, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0002-5246-4603
Michelle A WilliamsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-5807-5281
Marsha Wills-KarpCenter for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-7929-1362
Mohamed H ShamjiImmunomodulation and Tolerance Group, Allergy and Clinical Immunology, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-3425-3463
Kari C NadeauDepartment of Environmental Health, Harvard T. H. Chan. School of Public Health, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2146-2955

Funding

Treatment of Peanut Allergy with Intradermal Administration of ASP0892 (ARA-LAMP-vax): A Randomized, Double-Blind, Placebo-Controlled, Phase I/II StudyUM2AI130836 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KEET, CORINNE · 2017 to 2023
$62.1M
The effects of immune-age on immune-response and the molecular mechanisms which drive itP01AI153559 · NIAID · STANFORD UNIVERSITY · PI DAVIS, MARK MORRIS · 2021 to 2025
$17.8M
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierU01AI147462 · NIAID · STANFORD UNIVERSITY · PI Mary Johnson, GIDEON LACK · 2020 to 2026
$14.0M
MOLECULAR BASIS OF ALLERGIC AND IMMUNOLOGIC DISEASET32AI007512 · NIAID · CHILDREN'S HOSPITAL BOSTON · PI Janet Chou, Peter A Nigrovic · 1996 to 2026
$13.1M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
NIAID NIH HHS K24 AI106822NIAID NIH HHS P01 AI153559NIAID NIH HHS T32 AI007512NIAID NIH HHS U01 AI147462NIAID NIH HHS UM2 AI130836NIH HHS K24 AI106822NIH HHS P01AI153559NIH HHS T32 AI007512NIH HHS U01 AI147462NIH HHS UM2AI130836
6 · The paper itself

Abstract

Artificial intelligence (AI) in environmental health science is revolutionizing data analysis and problem-solving approaches. These technologies facilitate the prediction of environmental exposures and disease outcomes and enable the identification of causal relationships for subsequent hypothesis testing. AI techniques improve pollution research through the analysis of satellite imagery and the modeling of pollutant dispersion, while AI advances chemical safety evaluations in toxicology by examining extensive datasets. AI is instrumental in addressing pressing environmental challenges, including remediation of polluted sites and ensuring equitable healthcare applications to mitigate biases. The expanding availability of large-scale environmental, geospatial, and health outcome databases offers unprecedented opportunities for innovative applications. Their predictive capabilities are essential in disaster management, enabling real-time analysis and optimizing resource deployment amid climate-related crises. AI-driven approaches play a critical role in carbon capture and waste management efforts aimed at reducing environmental impact. Furthermore, AI can elucidate complex relationships between the exposome-defined as the totality of exposures throughout an individual's life-and health outcomes, facilitating preventative strategies. This review examines the capabilities and limitations of AI in environmental health and safety, providing insights into its judicious and effective use for environmental management and healthcare.

Indexed as

Allergy and ImmunologyArtificial IntelligenceAsthmaEnvironmental ExposureHypersensitivityEnvironmental HealthHumansallergyartificial intelligenceasthmaenvironmental healthmachine learning

Identifiers

PMID42233500
PMCPMC13569709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.