Evidence map›Paper›PMID 42233472›Full record

ArticleACS applied materials & interfaces2026

Salivary Enzyme-Responsive Switching Nanoparticles Overcoming Diffusion and Absorption Barriers for Transmucosal Delivery.

Se Kye Park, Lam Tan Hao, Hee Jung Park, Dong Yun Lee, Hyeonyeol Jeon, Hyo Jeong Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Se Kye ParkResearch Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan44429, Republic of Korea.
Lam Tan HaoResearch Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan44429, Republic of Korea.ORCID 0000-0001-9791-6071
Hee Jung ParkTechnical Support Center for Chemical Industry, Korea Research Institute of Chemical Technology (KRICT), Ulsan44429, Republic of Korea.
Dong Yun LeeDepartment of Polymer Science and Engineering, Kyungpook National University, Daegu41566, Republic of Korea.ORCID 0000-0003-4998-2116
Hyeonyeol JeonResearch Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan44429, Republic of Korea.ORCID 0000-0001-9176-2913
Hyo Jeong KimResearch Center for Bio-Based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan44429, Republic of Korea.ORCID 0000-0002-5331-5407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transmucosal drug delivery is an attractive noninvasive strategy, yet its efficiency is fundamentally limited by the trade-off between mucus penetration and mucoadhesion. Here, we present salivary enzyme-responsive penetration-to-adhesion switching nanoparticles (SEPAS NPs) designed to overcome this limitation in the context of buccal drug delivery. SEPAS NPs feature a dual-regime architecture consisting of an

Indexed as

NanoparticlesSalivaAnimalsCell LineChitosanDexamethasoneDiffusionDrug Delivery SystemsHumansKineticsMiceMucous MembraneChitosanDexamethasonebuccal drug deliveryguanidinium chitosan oligosaccharidemucoadhesionmucus penetrationsalivary enzyme-responsive

Identifiers

PMID42233472
PMCPMC13308602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.