ReviewBiochemical Society transactions2026
The primary cilium at the helm: gatekeeper of TGF-β superfamily signaling in development, homeostasis, and disease.
Review in Biochemical Society transactions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
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Abstract
The transforming growth factor-beta (TGF-β) superfamily is crucial for regulating cell proliferation, differentiation, migration, and tissue homeostasis, and plays a central role in embryonic development and function of tissues and organs. Dysregulation of these pathways contributes to a broad spectrum of diseases, including cancer, fibrosis, and developmental disorders. The present review explores how the primary cilium, a specialized signaling organelle, orchestrates TGF-β superfamily signaling, with a focus on emerging evidence of its role in heart and brain development, as well as in tissue homeostasis.
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