ArticleFrontiers in cellular and infection microbiology2026
Genomic characterization and niche adaptive analysis of
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Methods: A bacterial strain designated W2469 was isolated from the bile specimen of a patient with acute suppurative cholecystitis and cholecystolithiasis. Conventional phenotypic and molecular identification [matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), VITEK 2 biochemical assay, 16S ribosomal RNA (rRNA), and whole-genome sequencing (WGS)] was performed. Bioinformatics analyses, including average nucleotide identity (ANI), digital DNA-DNA hybridization (dDDH), core genome single-nucleotide polymorphism (cgSNP), pan-genome analysis, and functional annotation against COG, KEGG, CAZy, VFDB, and CARD databases, were conducted to characterize the strain. Results: Conventional methods yielded consistent misidentification of the strain, while WGS definitively assigned it to Conclusion: This study provides the first documentation of
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