ArticleIndian journal of palliative care
Comparative Effectiveness of Pharmacotherapy, Cognitive Behavioural Therapy and their Combination for Depression and Anxiety in Newly Diagnosed Cancer Patients: A 6-week Prospective Observational Study.
Article in Indian journal of palliative care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Despite the recent rise in cancer prevalence in India, psychological support is largely ignored. There is very less research on effectiveness of cognitive behavioural therapy (CBT) and pharmacotherapy (PT) as treatment options for psychological distress in cancer patients in India. So, this study was planned to evaluate the relative efficacy of PT, CBT, and their combination in reducing anxiety and depressive symptoms in newly diagnosed cancer patients referred for psychiatric evaluation at a tertiary care hospital in India. Materials and Methods: Between January 2022 and December 2024, newly diagnosed adult cancer patients referred for psychiatric evaluation were enrolled in the study. Of the 456 patients, 32 (6.9%) had a positive screening for generalised anxiety disorder and 75 (16.4%) for major depressive disorder. The Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, 5 Results: In the depression cohort ( Conclusion: Combined PT (SSRI) and CBT showed the most significant improvement in depression symptoms, while all treatment approaches provided comparable relief for anxiety. The study underlines the importance of integrated care in oncology and advocates a combined approach to treating cancer patients with depression and anxiety. Further research is needed to optimise treatments for anxiety, particularly in settings with limited resources.
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