Evidence map›Paper›PMID 42233039›Full record

ArticleFrontiers in sports and active living2026

Chronic anterior talofibular ligament rupture is associated with bilateral knee alterations and reduced ankle plantar flexor moment during gait.

Liufeng Xiao, Peiyao Liang, Lili Hu, Lin Guo, Lihang Zhang, Chengke Zhang, Molong Chen, Lisha Xu, Shikun Wen, Dianwei Li and 1 more

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Article in Frontiers in sports and active living, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Liufeng Xiao *Department of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Peiyao Liang *Department of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Lili Hu *Department of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Lin GuoDepartment of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Lihang ZhangDepartment of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Chengke ZhangDepartment of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Molong ChenDepartment of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Lisha Xu *Department of Public Health, and Department of National Clinical Research Center for Child Health, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shikun Wen *Department of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Dianwei Li *Department of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.
Lin MaDepartment of Orthopedics/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With the increasing clinical burden of ankle injuries, particularly anterior talofibular ligament (ATFL) rupture, understanding their biomechanical impact on gait has gained renewed importance. While previous research has established local ankle deficits, the specific proximal compensatory mechanisms-particularly at the knee joint-in patients with MRI-confirmed complete ligamentous discontinuity remain insufficiently characterized. Purpose: The objective of this study was to investigate spatiotemporal and kinetic alterations in ankle and knee biomechanics in individuals with chronic ligament insufficiency during walking compared to normal controls. Methods: A total of 78 participants were enrolled in Southwest Hospital. The injury group consisted of 39 individuals with MRI-confirmed complete ATFL rupture scheduled for surgery, recruited from a specialized sports medicine clinic. They were matched with 39 healthy controls. Three-dimensional motion capture synchronized with force plates was used to assess gait parameters, including step/stance times, ground reaction forces, joint angles, and moments. Results: Patients with ATFL rupture exhibited significantly reduced stride length compared to controls ( Conclusion: Individuals with chronic ATFL rupture exhibit persistent gait asymmetries and altered lower-limb biomechanics, including reduced stride length, diminished ankle plantar flexor moment, and modified kinematics at both the injured and contralateral knee joints. These findings suggest that functional deficits may extend beyond the ankle to affect proximal joints along the kinetic chain. Although the cross-sectional design precludes causal inference, the observed bilateral kinematic alterations at the knee suggest that proximal joint adaptations may accompany chronic ATFL rupture and warrant further investigation in prospective and interventional studies.

Indexed as

chronic anterior talofibular ligament insufficiencygait analysisjoint kineticskinematic alterationlower extremity biomechanics

Identifiers

PMID42233039
PMCPMC13223045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.