Evidence map›Paper›PMID 42232996›Full record

ArticleFrontiers in psychiatry2026

High functioning, yet high suffering - the need to incorporate invisible struggles in adult ADHD diagnostic assessment/criteria.

Ines Homem de Melo, Gustavo Franca

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ines Homem de MeloClínica do Quinto Andar, Porto, Portugal.
Gustavo FrancaClínica do Quinto Andar, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current DSM-5 diagnostic criteria for adult Attention-Deficit/Hyperactivity Disorder (ADHD) rely predominantly on externally observable signs and measurable functional impairment. While prior literature has criticized the child-centric and male-centric biases embedded in this framework, less attention has been given to its sign-centric and impairment-centric orientation. In this perspective article, we argue that this emphasis creates a critical diagnostic blind spot: adults who maintain high academic, occupational, or social performance through compensatory strategies and masking, yet experience substantial internal suffering. For these individuals, impairment is not absent but concealed beneath sustained effort, perfectionistic overcompensation, and chronic self-monitoring. The resulting psychological burden, emotional exhaustion, anxiety, shame, cognitive fatigue, and diminished quality of life often remain invisible within behavior-based diagnostic systems. We contend that current criteria capture the end-products of ADHD (observable behaviors and overt dysfunction) while neglecting the upstream processes shaping lived experience. Phenomena such as mind-wandering, internal restlessness, time blindness, sensory over-responsivity, and effortful self-regulation are clinically meaningful yet insufficiently represented in formal criteria. Moreover, compensatory mechanisms and masking, despite their relevance to clinical presentation and diagnostic accuracy, are not systematically assessed. We propose a process-based expansion of adult ADHD assessment that incorporates subjective cognitive phenomena, explicit evaluation of masking and compensatory strategies, and recognition of subjective distress and effort-to-output imbalance as diagnostically relevant dimensions. Such a paradigm shift would enhance diagnostic sensitivity, reduce misdiagnosis and underrecognition - particularly among high-functioning adults and women - and promote more equitable access to appropriate care. Recognizing invisible struggles is essential to capturing the full heterogeneity and lived reality of adult ADHD.

Indexed as

ADHD (attention deficit and hyperactivity disorder)ADHD diagnosis in adultscompensatory mechanismsdiagnostic assessmenthigh-functioning ADHDlived experiencemaskingneurodevelopmental disorders

Identifiers

PMID42232996
PMCPMC13224461

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.