Evidence map›Paper›PMID 42232842›Full record

ArticleJournal of contemporary brachytherapy2026

Enhancing brachytherapy in cervical cancer: Initial dosimetric experience and assessment of Tulip hybrid applicator - the Add-On advantage.

Ayesha Iqbal Maniyar, Ram Charith Alva, Kirthi Koushik, Sagarika Nithyanand, M G Janaki, P Revathy, T R Arul Ponni, Mohan Kumar, M Lithika Lavanya

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ayesha Iqbal ManiyarAster International Institute of Oncology (AIIO), Bengaluru, India.
Ram Charith AlvaAster International Institute of Oncology (AIIO), Bengaluru, India.
Kirthi KoushikM. S. Ramaiah Medical College and Hospital, Bengaluru, India.
Sagarika NithyanandAster International Institute of Oncology (AIIO), Bengaluru, India.
M G JanakiDepartment of Radiation Oncology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India.
P RevathyDepartment of Radiation Oncology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India.
T R Arul PonniDepartment of Radiation Oncology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India.
Mohan KumarDepartment of Radiation Oncology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India.
M Lithika LavanyaDepartment of Radiation Oncology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report initial clinical experience of the Tulip Add-On hybrid intracavitary/interstitial (IC/IS) brachytherapy applicator in locally advanced carcinoma cervix, and to compare its dosimetric performance with conventional IC brachytherapy. Material and methods: Eight patients with FIGO stage IIB-IIICr1 cervical cancer were treated between January 2021 and January 2022. All received external beam radiotherapy with concurrent chemotherapy, followed by CT-guided IC/IS brachytherapy using Henschke applicator with Tulip Add-On interstitial needles. Paired dosimetric plans (IC/IS vs. IC-only) were generated for each patient. Target coverage (D Results: Median age was 58 years; median high-risk clinical target volume (HR-CTV) was 55.6 cc (range, 25.6-81 cc). Six patients required bilateral and two unilateral interstitial insertions. Compared with IC-only, IC/IS plans significantly improved HR-CTV coverage: D Conclusions: The Tulip Add-On applicator offers superior HR-CTV coverage without compromising OARs sparing. It is a practical, resource-adaptive technique that combines simplicity of intracavitary brachytherapy with dosimetric advantages of interstitial approaches, particularly valuable for patients with residual parametrial disease post-EBRT.

Indexed as

cervical cancerhybrid brachytherapyICRU 38ICRU 58ICRU 89IGABTimage-guided brachytherapy

Identifiers

PMID42232842
PMCPMC13225089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.