ArticleSensors and actuators. B, Chemical2026
A Universal Optical Microanalysis Platform Based on Micropipette Tips.
Article in Sensors and actuators. B, Chemical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Low-Frequency Segmented-Flow Microfluidics for Biphasic Chemical Sensing.Sensors and actuators. B, Chemical · 2026Article
- Millifluidic ion-selective optodes with integrated optical detection for colorimetric quantification of urinary calcium.Talanta · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The need for automated analytical devices capable of handling low-volume samples remains a major challenge in medical diagnostics, biomedical research, and environmental studies. Although microfluidic systems have shown promise, their broader adoption has been limited by challenges such as intricate chip fabrication, cumbersome sample loading, limited detector integration, and significant dead volumes. Herein, we report a micropipette tip-based Lab-on-a-Tip platform that integrates fluid handling, reagent loading, chemical reaction, and optical detection within a single, modular unit. The system couples a low-cost multispectral photodiode directly to the pipette tip, enabling multi-channel absorbance and fluorescence measurements in a few microliters of samples. Fluid manipulation is automated using a programmable pipette, allowing chemical and biochemical assays to be conducted within pipette tips preloaded with reagents. The inherent advantages of pipette tips, such as affordability, optical clarity, solvent compatibility, precise fluid control, and flexible conical geometry, distinguish them from traditional microfluidic chips. The capability of the platform is demonstrated through a series of assays, including enzymatic reaction monitoring, biochemical sensing with molecular probes, biphasic detection with oil sensors, and multi-step chemical analyses. By streamlining workflows, minimizing reagent consumption, eliminating dead volumes, and enhancing portability, Lab-on-a-Tip offers a transformative solution for compact, high-performance analytical systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.