ArticleJHLT open2026
Early predictors and outcomes of mechanical circulatory support use during single lung transplant for secondary pulmonary hypertension: A large single-center experience.
Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Minimal data exists to predict the need for mechanical circulatory support (MCS) for patients with secondary pulmonary hypertension (SPH) undergoing single lung transplant (SLT). We aim to identify preoperative hemodynamic and echocardiographic variables that could predict MCS use and compare clinical outcomes for SLT with and without intraoperative MCS use. Methods: An institutional registry of SLT recipients with SPH between 2017 and 2021 were analyzed. Cohorts were separated by the use of intra-operative MCS and analyzed. Odds ratios and multivariable logistic regression were utilized to evaluate the likelihood of requiring intraoperative MCS during SLT. Results: We identified 293 patients, of which 44 (15.1%) required intraoperative MCS use, while 249 (84.9%) did not. Preoperative RV-PA coupling ratio or TAPSE/PASP ratio <0.3 was highly associated with intraoperative MCS use during SLT (OR4.09 (95% 2.06 - 8.14, p=<0.0001). PCWP, pre-operative PVR, transplant laterality, LAS and intraoperative PA Systolic Pressure were also independently associated with intraoperative MCS use. Length of stay was longer in the MCS-use group (29.8 vs 18.5 days, p= 0.007) whereas survival was similar at 30 (100% MCS vs 99.6% non-MCS, p=1) and 60 days (100% MCS vs 98% non-MCS, p=0.75). A Kaplan-Meier analysis showed no survival difference to 3 years (p=0.92). Conclusions: Assessment of preoperative RV-PA uncoupling using TAPSE/PASP ratio can help predict intraoperative MCS use during SLT. A preoperative TAPSE/PASP <0.3 confers a 4-fold increase in the likelihood of MCS use. The use of MCS during SLT does increase the length of stay, however, does not significantly change survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.