ArticleFood & nutrition research2026
Salivary cortisol dynamics and their relationship with sleep and mental well-being in adults receiving a phospholipid-based
Article in Food & nutrition research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, as indicated by altered salivary cortisol secretion, has been linked to poor sleep quality, mood disturbances, and emotional distress. In the principal clinical trial, 3 weeks of Melissa phospholipids' supplementation was associated with significant improvements in sleep quality and mood outcomes. Objective: This study aimed to evaluate salivary cortisol dynamics in a subpopulation supplemented with Design: This secondary analysis evaluated a predefined subgroup ( Results: Mean salivary cortisol levels decreased progressively over the 3-week supplementation period, with a significant main effect of time ( Discussion and conclusions: This secondary analysis provides preliminary evidence that Melissa phospholipids supplementation, is associated with a significant modulation of HPA axis activity, characterized by a reduction in daily salivary cortisol levels, in adults with poor sleep quality and emotional distress.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.