ArticleCase reports in oncology
Long-Term Survival following Trimodal Therapy Including Hyperfractionated Radiotherapy in Parotid NUT Carcinoma: A 29-Month Follow-Up Case Report.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: NUT carcinoma (NC) is a rare, aggressive malignancy with median survival below 1 year. Reports of long-term survival are exceptional and rare. While multimodal treatment strategies including surgery, radiotherapy, and chemotherapy have been attempted, evidence remains scarce. Case Presentation: We report the case of a middle-aged female patient with parotid NC harboring a NSD3::NUTM1 fusion. Following surgical resection, rapid disease progression with newly evident lymph node metastases occurred within 3 weeks, prompting definitive hyperfractionated intensity-modulated radiotherapy using a simultaneous integrated boost technique (1.4 Gy/1.6 Gy to 56.0 Gy/64 Gy, twice daily, 40 fractions) with concurrent weekly cisplatin (50 mg/m Conclusion: The present case suggests that hyperfractionated radiotherapy, exploiting radiobiological advantages in rapidly proliferating tumors, may improve both tumor control and toxicity profile compared to conventional fractionation in NC, warranting further investigation. To our knowledge, this represents one of the very few reports of a parotid NC patient achieving disease-free survival beyond 2 years after trimodal therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.