ArticleFrontiers in pediatrics2026
A prediction nomogram for faltering catch-up growth in full-term small-for-gestational-age infants: a retrospective cohort study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and objective: Catch-up growth (CUG) before two years of age in small-for-gestational-age (SGA) infants is a key predictor of adult short stature. We aimed to establish and temporally validate a prediction nomogram for faltering CUG (FCUG) in full-term SGA infants before two years of age. Methods: We conducted a retrospective cohort study of full-term SGA infants at West China Second University Hospital, with cohorts defined as: development (January 1996-December 2019) and temporal validation (January 2020-July 2023). Full-term SGA infants, defined by birth weight or length below 10th percentile per INTERGROWTH-21st standards ( Results: In the development cohort, 280 of 1,185 (23.6%) of SGA infants experienced FCUG before age two, compared with 60 of 294 (20.4%) in the temporal validation cohort. In multivariable logistic regression analyses, male sex, lower birth length Conclusions: We have developed and temporally validated a clinically applicable nomogram that reliably identifies full-term SGA infants at high risk of failing to achieve catch-up growth by age two. With robust discrimination and calibration, this tool can support early risk stratification and guide targeted nutritional or developmental interventions.
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