Evidence map›Paper›PMID 42232556›Full record

ArticleFrontiers in oncology2026

Case Report: The revelation of a new pathogenic variant in the POT1 gene in a patient with a pediatric high-grade glioma and a renal cell carcinoma.

Selene Cipri, Antonella Cacchione, Annalisa Serra, Giada Del Baldo, Evelina Miele, Lucia Pedace, Sara Patrizi, Federica D'Antonio, Emanuele Agolini, Antonio Novelli and 10 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Selene Cipri *Hematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Antonella Cacchione *Hematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Annalisa SerraHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Giada Del BaldoHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Evelina MieleHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Lucia PedaceHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Sara PatriziHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Federica D'AntonioHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Emanuele AgoliniLaboratory of Medical Genetics Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Antonio NovelliLaboratory of Medical Genetics Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Alessandro CrocoliEmergency General Surgery, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Arianna BertocchiniEmergency General Surgery, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Andrea CaraiNeurosurgery Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Sabina BarresiPathological Anatomy Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Sabrina RossiPathological Anatomy Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Rita AlaggioPathological Anatomy Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Francesca Diomedi CamasseiPathological Anatomy Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Giovanna Stefania ColafatiNuclear Medicine Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Luigi BoccutoSchool of Nursing, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, SC, United States.
Angela MastronuzziHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant Area, Bambino Gesù Pediatric Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to describe and molecularly characterize a rare case of early-onset multiple primary tumors associated with a novel germline

Indexed as

brain tumorscancer predisposition syndromehigh-grade gliomakidney cancerPOT1

Identifiers

PMID42232556
PMCPMC13222780

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.