Evidence map›Paper›PMID 42232534›Full record

SynthesisFrontiers in oncology2026

Influencing factors of fertility concerns in cancer patients of childbearing age: a systematic review and meta-analysis.

Yaxin Wang, Renmei Yang, Zhaoli Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yaxin WangDepartment of Thoracic Tumor Center, Chongqing University Cancer Hospital, Chongqing, China.
Renmei YangDepartment of Thoracic Tumor Center, Chongqing University Cancer Hospital, Chongqing, China.
Zhaoli ZhangNursing Department, Chongqing University Cancer Hospital, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study systematically analyzes factors influencing fertility concerns among cancer patients to inform clinical practice. Methods: We conducted a comprehensive search of PubMed, Web of Science, Embase, Cochrane Library, and Scopus from inception through August 2024 for studies examining factors associated with fertility concerns in cancer patients. Two researchers independently performed literature screening, data extraction, and quality assessment. Meta-analyses were conducted using RevMan 5.4 and Stata 17.0. Results: A total of 13 articles were included, including 11 cross-sectional studies and 2 longitudinal studies, including 3282 patients. which showed that depression ( Conclusions: This study provides the first quantitative evidence that endocrine therapy and prior fertility counseling are significantly associated with elevated fertility concerns, highlighting potential clinical paradoxes and the complex interplay between medical intervention and psychological distress. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42024582238.

Indexed as

associated factorscancerfertility concernsmeta-analysissystematic review

Identifiers

PMID42232534
PMCPMC13223885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.