ArticleSurgical neurology international2026
Network-guided resection of magnetic resonance imaging-negative mesial temporal epilepsy using gamma oscillation regularity-based transfer entropy analysis.
Article in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Medically refractory, magnetic resonance imaging (MRI)-negative mesial temporal lobe epilepsy presents a diagnostic challenge, often leading to difficulties in localizing the epileptogenic zone and planning effective surgical strategies. Case Description: We present a case in which complementary preoperative and intraoperative electrophysiological analyses identified an occult epileptogenic focus. Preoperative high-density scalp electroencephalogram evaluated with gamma oscillation regularity (GOR) analysis localized a putative epileptogenic region adjacent to the hippocampus. Guided by this localization, intraoperative electrocorticography was analyzed using GOR-based transfer entropy (TE). This mapping revealed a compact hub of consistent outgoing directed information flow localized to the parahippocampal gyrus. The surgical strategy targeted the GOR-based TE-defined parahippocampal focus and its immediate efferent connections while preserving the hippocampus. The patient remains seizure-free with preserved neurocognitive function at follow-up. Conclusion: This case demonstrates that preoperative GOR analysis can noninvasively direct focused intraoperative network interrogation and that GOR-based TE-derived directed connectivity mapping can unmask mesial temporal epileptogenicity in MRI-negative cases, thereby guiding effective, tissue-sparing resections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.