Evidence map›Paper›PMID 42232352›Full record

ArticleCase reports in perinatal medicine2026

Acute pulmonary edema secondary to magnesium sulfate tocolysis in twin pregnancy: a case report.

Xiaoling Liang, Jiaxin Kang, Bowen Zheng, Yicong Liao, Shiqing Wang, Guoliang Yan, Junxiang Jia

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Article in Case reports in perinatal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Xiaoling LiangDepartment of Anesthesiology, Department of Obstetrics and Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Jiaxin KangSchool of Medicine, Xiamen University, Xiamen, Fujian, China.
Bowen ZhengSchool of Medicine, Xiamen University, Xiamen, Fujian, China.
Yicong LiaoDepartment of Anesthesiology, Department of Obstetrics and Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Shiqing WangDepartment of Anesthesiology, Department of Obstetrics and Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Guoliang YanSchool of Medicine, Xiamen University, Xiamen, Fujian, China.
Junxiang JiaDepartment of Anesthesiology, Department of Obstetrics and Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Acute pulmonary edema during pregnancy is a rare but serious complication, particularly in association with magnesium sulfate therapy for tocolysis. This case report describes a 27-year-old woman with a twin pregnancy who developed acute pulmonary edema after 3 days of magnesium sulfate treatment. Case presentation: The patient presented with chest tightness, dyspnea, and respiratory distress. Immediate clinical intervention included discontinuation of magnesium sulfate and administration of furosemide to reduce cardiac preload. She was managed with diuretics, sedatives, and inotropic agents. Both infants were delivered successfully, and the patient recovered after supportive care in the intensive care unit. Conclusions: This case highlights the potential risks of fluid retention and the importance of monitoring maternal fluid status during tocolysis. It also emphasizes the need for vigilance in managing twin pregnancies with magnesium sulfate therapy to prevent serious complications such as pulmonary edema. Clinicians should be aware of this rare but potentially life-threatening complication and ensure that fluid balance is carefully monitored in such cases.

Indexed as

magnesium sulfatematernal healthperinatal complicationspulmonary edematocolysistwin pregnancy

Identifiers

PMID42232352
PMCPMC13225067

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