Evidence map›Paper›PMID 42232257›Full record

ArticleJournal of visualized surgery2025

Abruzzini procedure: transsternal bronchial closure for left bronchopleural fistula post-pneumonectomy.

José de Sá Moraes Neto, Murilo Fernandes de Souza, Paulo Manuel Pego-Fernandes, Alessandro Wasum Mariani

Abstract read
In one paragraph

Article in Journal of visualized surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

José de Sá Moraes NetoDepartment of Thoracic Surgery, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0005-2367-1514
Murilo Fernandes de SouzaDepartment of Thoracic Surgery, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0008-8194-9512
Paulo Manuel Pego-FernandesDepartment of Thoracic Surgery, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-7243-5343
Alessandro Wasum MarianiDepartment of Thoracic Surgery, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-3004-1351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchopleural fistula (BPF) is a rare but severe complication following pneumonectomy, associated with high morbidity and mortality, particularly when pleural contamination occurs. Several predisposing factors have been described, including preoperative corticosteroid use, right-sided pneumonectomy, neoadjuvant therapy, diabetes mellitus, and the presence of a long bronchial stump. Preventive strategies such as bronchial stump reinforcement have been widely employed, though the optimal technique and material remain controversial. Therapeutic options range from minimally invasive approaches, including endobronchial closure with cauterization or biological glue, to complex surgical procedures such as intrathoracic muscle transposition, thoracostomy, and thoracoplasty. In cases where conventional reclosure of the stump is hindered by infection or adhesions, the transsternal transpericardial approach described by Abruzzini in 1961 offers an alternative that avoids direct manipulation of the infected pleural cavity. This technique enables safe exposure of the mediastinal structures through a full median sternotomy, allowing direct closure of the bronchial stump. The present study provides a descriptive account and educational video of the Abruzzini technique, based on a real clinical case. The patient, a 72-year-old male with silicosis and endobronchial aspergilloma, underwent left pneumonectomy with radical mediastinal lymphadenectomy. Postoperative evolution was complicated by stump dehiscence and recurrent BPF, despite previous surgical attempts with manual suturing and thymic flap reinforcement. Definitive management was achieved through the transsternal transpericardial approach, involving careful mediastinal dissection, protection of major vascular structures, and closure of the bronchial stump with stapling under bronchoscopic guidance. This report emphasizes the technical nuances of the procedure, including the impact of mediastinal shift in left pneumonectomy, the risks of vascular injury, and the necessity of meticulous preoperative imaging. Differences between left- and right-sided fistulas are also highlighted, underscoring the importance of individualized surgical planning. BPF remains one of the most challenging post-pneumonectomy complications, with mortality exceeding 50% in uncontrolled cases. Although rarely performed, the Abruzzini technique remains a valuable tool in selected scenarios, with reported success rates above 80%. By documenting this surgical approach through video demonstration, the present work aims to enhance thoracic surgery training, preserve classical techniques, and promote safer management of complex BPF.

Indexed as

AbruzziniBronchopleural fistula (BPF)pneumonectomy

Identifiers

PMID42232257
PMCPMC13224998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.