Evidence map›Paper›PMID 42232015›Full record

ReviewCureus2026

Gut or Vein? Enteral Nutrition Versus Total Parenteral Nutrition in Acute Pancreatitis: A Systematic Review.

Harnoor Kaur, Archit Sharma, Palangutde Katherine Dimowo, Akshay Rajeev, Sabah Shakeel Shaikh, Lubna Mohammed

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Harnoor KaurInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, California, USA.
Archit SharmaPaediatrics, Wrightington Wigan Leigh Hospitals NHS Foundation Trust, Wigan, GBR.
Palangutde Katherine DimowoOtolaryngology - Head and Neck Surgery, California Institute of Behavioral Neurosciences & Psychology, California, USA.
Akshay RajeevHematology, Great Western Hospital, Swindon, GBR.
Sabah Shakeel ShaikhDiabetes and Endocrinology, California Institute of Behavioral Neurosciences & Psychology, California, USA.
Lubna MohammedPrinciples and Practice of Clinical Research, Harvard School of Public Health, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis is a common inflammatory condition with significant morbidity and mortality, particularly in patients who progress to moderately severe or severe disease. Nutritional support is an essential aspect of management, although the optimal route of nutrition remains debated. This systematic review assessed whether enteral nutrition (EN), compared with total parenteral nutrition (TPN), is associated with improved clinical outcomes in patients with acute pancreatitis. A thorough literature search was conducted across multiple electronic databases in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, including studies published between 1/01/2010 and 22/11/2025. A total of 1,480 records were identified, of which 1,382 records were screened after duplicate removal. Following title, abstract, and full text assessment, six studies met the predefined inclusion criteria and quality standards and were included in the final analysis. Eligible studies included human patients with acute pancreatitis that directly compared EN with TPN and reported clinically relevant outcomes such as morbidity and mortality. Study selection, data extraction, and quality appraisal were conducted using validated tools, including version 2 of

Indexed as

acute pancreatitisacute pancreatitis complicationsearly enteral nutrition (een)enteral and parenteral nutritionenteral nutrition (en)severe acute pancreatitistotal parenteral nutrition (tpn)

Identifiers

PMID42232015
PMCPMC13222748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.