Evidence map›Paper›PMID 42231765›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Mitochondria-Damaging Self-Reporting Probe for Cancer Therapy.

Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam and 1 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hai XuDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, Republic of Korea.ORCID 0000-0002-8270-9341
Yura LeeDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Sanghee YoonGlobal AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.ORCID 0000-0003-1882-887X
Yun WangLaboratory of Human Disease and Immunotherapies, West China Hospital, Sichuan University, Chengdu, P. R. China.
Yejin ChoDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Seongyu ChoiDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Lu LuSchool of Chemistry and Chemical Engineering, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Henan Normal University, Henan, P. R. China.
Hua ZhangSchool of Chemistry and Chemical Engineering, Henan International Joint Laboratory of Smart Molecules and Identification and Diagnostic Functions, Henan Normal University, Henan, P. R. China.ORCID 0000-0002-7593-4946
Sun ChoiGlobal AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Republic of Korea.ORCID 0000-0002-7669-7954
Ki Taek NamDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-5292-1280
Juyoung YoonDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul, Republic of Korea.ORCID 0000-0002-1728-3970

Funding

Korea Basic Science InstituteNational Natural Science Foundation of China 22574041National Natural Science Foundation of China U25A20619National Research Foundation of Korea RS-2024-00407093National Research Foundation of Korea RS-2026-25477010
6 · The paper itself

Abstract

Mitochondrial damage induced by chemotherapeutic agents through disruption of the mitochondrial membrane potential (ΔΨ

Indexed as

Antineoplastic AgentsFluorescent DyesMitochondriaNeoplasmsAnimalsApoptosisDrug Screening Assays, AntitumorFluorescent Chemosensor CompoundsHumansMembrane Potential, MitochondrialMiceReactive Oxygen SpeciesAntineoplastic AgentsFluorescent Chemosensor CompoundsFluorescent DyesReactive Oxygen Speciescancer therapyfluorescence imagingmitochondriaself‐reporting probe

Identifiers

PMID42231765
PMCPMC13427109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.