ArticleJournal of anesthesia, analgesia and critical care2026
Intraoperative mechanical power and postoperative pulmonary complications: association and threshold analysis in adult intra-abdominal surgery.
Article in Journal of anesthesia, analgesia and critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
backgroundPostoperative pulmonary complications (PPCs) contribute to perioperative morbidity and mortality. Mechanical powers (MPs) determined using different deviations from originally described MP have been shown to be associated with PPCs. We aimed to evaluate the association between a standardized derivation of MP and PPCs and to explore a threshold associated with increased risk in multicentre cohort of adults undergoing intra-abdominal surgery.
methodsData on adult patients who underwent intra-abdominal surgery under general anaesthesia were obtained from the Multicentre Perioperative Outcomes Group registry. The primary outcome was a composite of PPCs comprising an expanded subset of diagnoses consistent with European Perioperative Clinical Outcome definitions. The association between intraoperative MP and PPCs was evaluated using multivariable logistic regression, adjusting for patient, surgical, and institutional factors.
resultsAmong 79,149 patients from 56 institutions, 4,812 (6.1%) developed PPCs. Each 1 J/ min increase in MP was associated with 5% higher odds of PPCs (OR = 1.05, 95% CI [1.05-1.06]; p < 0.0001). Receiver operating characteristic analysis identified a threshold of 12 J/ min (sensitivity = 0.54, specificity = 0.51), above which patients had 54% higher adjusted odds of PPCs (OR
conclusionsHigher MP was associated with increased risk of PPCs in patients undergoing intra-abdominal surgery. Although MP values above 12 J min⁻
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