Evidence map›Paper›PMID 42231462›Full record

ArticleBMC chemistry2026

New benzoxanthenone and benzanthrone derivatives from Tricholaena teneriffae L. roots: structure elucidation, α-amylase inhibitory activity and molecular docking studies.

Henda Keskes, Ines Dhouib, Emna Khdhiri, Houcine Ammar, Anthony Abou Dib, Jean-Hugues Renault, Noureddine Allouche, Bassem Khemakhem, Hichem Ben Salah

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Article in BMC chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Henda KeskesLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, P.O. Box 1171, 3000, Sfax, Tunisia.
Ines DhouibLaboratory of Plant Biotechnology, Faculty of Sciences of Sfax, University of Sfax, BP 1171, 3038, Sfax, Tunisia.
Emna KhdhiriLaboratory of Applied Chemistry: Heterocycles, Fatty Compounds and Polymers, Faculty of Sciences, University of Sfax, 3038, Sfax, Tunisia.
Houcine AmmarLaboratory of Applied Chemistry: Heterocycles, Fatty Compounds and Polymers, Faculty of Sciences, University of Sfax, 3038, Sfax, Tunisia.
Anthony Abou DibCNRS, ICMR UMR 7312, Université de Reims Champagne Ardenne, Reims, France.
Jean-Hugues RenaultCNRS, ICMR UMR 7312, Université de Reims Champagne Ardenne, Reims, France.
Noureddine AlloucheLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, P.O. Box 1171, 3000, Sfax, Tunisia. noureddineallouche@yahoo.fr.
Bassem KhemakhemLaboratory of Plant Biotechnology, Faculty of Sciences of Sfax, University of Sfax, BP 1171, 3038, Sfax, Tunisia.
Hichem Ben SalahLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, P.O. Box 1171, 3000, Sfax, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ethyl acetate extract of Tricholaena teneriffae L. roots exhibited significant α-amylase inhibitory activity. Phytochemical analysis of this extract led to the isolation of seven natural products: five 12H-benzo[a]xanthen-12-one derivatives (1-5) and two 7H-benzo[de]anthracen-7-one derivatives (6-7). Among them, compounds 1, 3, 4, 5, and 7 are reported here for the first time as new natural derivatives. Structural elucidation was performed via 1D and 2D NMR spectroscopy, allowing for a precise determination of the substitution patterns of both the benzo[a]xanthen-12-one and benzo[de]anthracen-7-one frameworks. Among them, compounds 6 (IC

Indexed as

12H-benzo[a]xanthen-12-one derivatives7H-benzo[de]anthracen-7-one derivativesFluorescenceMolecular dockingRootsTricholaena teneriffaeα-Amylase inhibition

Identifiers

PMID42231462
PMCPMC13466186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.