Evidence map›Paper›PMID 42231381›Full record

ArticleHarm reduction journal2026

Implementation and sustainability of hospital-based harm reduction delivery: a qualitative analysis.

Leslie W Suen, Leah Fraimow-Wong, Taylor Baisey, Kelly R Knight, Laura Thomas, Ro Giuliano, Oanh Kieu Nguyen, Marlene Martín

Abstract read
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Article in Harm reduction journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Leslie W SuenDivision of General Internal Medicine, Department of Medicine, San Francisco General Hospital, University of California San Francisco, 2540 23rd Street, Floor 4, Room 4316, San Francisco, CA, 94143, USA. Leslie.suen@ucsf.edu.ORCID https://orcid.org/0000-0003-4786-356X
Leah Fraimow-WongDivision of General Internal Medicine, Department of Medicine, San Francisco General Hospital, University of California San Francisco, 2540 23rd Street, Floor 4, Room 4316, San Francisco, CA, 94143, USA.
Taylor BaiseyDivision of Hospital Medicine, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
Kelly R KnightDepartment of Humanities and Social Sciences, University of California San Francisco, San Francisco, CA, USA.
Laura ThomasSan Francisco AIDS Foundation, San Francisco, CA, USA.
Ro GiulianoSan Francisco AIDS Foundation, San Francisco, CA, USA.
Oanh Kieu NguyenDivision of Hospital Medicine, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
Marlene MartínDivision of Hospital Medicine, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.

Funding

A Longitudinal Qualitative Study of Fentanyl-Stimulant Polysubstance Use Among People Experiencing Homelessness (Administrative supplement)R01DA057672 · NIDA · YALE UNIVERSITY · PI KNIGHT, KELLY RAY, MCNEIL, RYAN · 2022 to 2023
$2.7M
AHRQ HHS K12HS026383NIDA NIH HHS R01DA057672
6 · The paper itself

Abstract

backgroundPatients with substance use disorders (SUD) face several challenges when hospitalized, including stigma, undertreated withdrawal and pain, and higher rates of self-directed discharge. Hospital-based harm reduction services can support patients with SUD, increase engagement, build trust, and catalyze culture change. Our hospital's Addiction Consult Team implemented a harm reduction program to provide education and substance use equipment to hospitalized patients whose SUD goals did not include abstinence. We conducted a qualitative evaluation of our harm reduction program to identify implementation and sustainability themes for long-term success.

methodsThis qualitative study consisted of semi-structured interviews conducted between October 2022 and March 2023 with hospitalized patients receiving harm reduction services and hospital staff at an urban safety-net hospital in San Francisco, California. Interviews were audio-recorded and transcribed with informed participant consent. Transcripts were deductively and inductively coded through an iterative process, and we used thematic analysis to identify themes.

resultsWe interviewed 20 patients and 20 staff participants with interviews ranging from 30-45 min. We identified three themes related to implementation and three related to sustainability. Implementation themes were: (1) Operational barriers, including time constraints, lack of clearly defined roles, and competing demands, challenged delivery of harm reduction kits; (2) Tension between generalized versus specialized harm reduction program ownership limited impact; and (3) Educational gaps impeded broader harm reduction uptake and reinforced stigma. Sustainability themes were: (1) Experiential learning reinforced harm reduction practice and culture change; (2) Interprofessional collaboration, especially involving SUD champions, supported the program; and (3) Sharing patient success stories helped overcome stigma and burnout and highlighted harm reduction effectiveness.

conclusionHarm reduction program implementation was challenged by resource constraints, complexity of program ownership, and lack of SUD knowledge. In contrast, experiential learning, interprofessional collaboration, and sharing patient successes sustained harm reduction efforts. Based on these findings, we recommend the following for long-term harm reduction program success: operationalize harm reduction workflow via hospital-wide interprofessional efforts; incorporate continuous, multimodal substance use training with all staff to ensure a baseline knowledge and drive culture change; and create feedback processes to share patient outcomes and narratives with staff.

Indexed as

Harm ReductionSubstance-Related DisordersAdultFemaleHumansMaleMiddle AgedProgram EvaluationQualitative ResearchSafety-net ProvidersSan FranciscoHarm reduction servicesIn-patientQualitative studySafety-net hospitalSemi-structured interviewsThematic analysis

Identifiers

PMID42231381
PMCPMC13445902

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.