ArticleBMC musculoskeletal disorders2026
Association of lumbar vertebral hemangiomas with low back pain, morphological changes, and quality of life: a cross-sectional study.
Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
objectiveVertebral hemangiomas are common benign spinal lesions. But studies of lumbar vertebral hemangiomas (LVHs) are still relatively limited. In this work, we assessed the distribution of LVHs within the study population, and explored their relationships with different categories of low back pain (LBP), pain- and health-related outcomes, and lumbar spine morphology.
methodsA retrospective cross-sectional study recruited 1,021 participants with or without LBP. Magnetic resonance imaging was used to assess the location, size as well as types of LVHs. Clinical data were collected from well-designed questionnaires and clinical examination.
resultsLVHs were identified in 8.3% of the recruited participants, and their prevalence increased with advancing age. The prevalence of LVHs differed across back pian categories, with rates of 12.4% in intermittent LBP groups, 10.0% in chronic LBP group, and 6.3% in the no back pain group. No statistically significant associations were observed between LVHs and either intermittent LBP (OR 1.96, p = 0.061) or chronic LBP (OR 1.40, p = 0.312). Additionally, pain intensity (p = 0.401), functional impairment (p = 0.110), and quality of life (p = 0.670) did not differ significantly between the no-LVHs and LVHs groups. Across different LBP categories, no significant difference in LVHs size, type, or number were observed among participants. Following age- and sex-adjusted propensity score matching, greater lumbar disc degeneration (p = 0.004) and a trend toward a higher prevalence of Modic changes (p = 0.060) were observed in participants with LVHs. No significant differences were found in facet joint degeneration, disc herniation, spinal canal width, or Schmorl's nodes between the LVHs and matched groups.
conclusionIn our study, LVHs were not associated with differences in LBP categories or health-related indicators. Additionally, participants with LVHs showed more severe lumbar disc degeneration but no other morphological abnormalities. LEVEL OF EVIDENCE: Level 3.
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