Trial reportBMC endocrine disorders2026
The effect of high intensity interval training on free androgen index in patients with polycystic ovary syndrome.
Trial report in BMC endocrine disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
backgroundPolycystic ovary syndrome (PCOS) is a multifactorial disorder characterized by hyperandrogenism, ovulatory dysfunction, and metabolic disturbances. Physical exercise is known to improve metabolic and hormonal profiles, yet the optimal type and intensity remain unclear.
objectiveTo compare the effects of high-intensity interval training (HIIT) versus regular-intensity training (RIT) on the free androgen index (FAI) and other hormonal and metabolic parameters in women with PCOS.
methodsForty-eight women with PCOS were randomly assigned to a 12-week supervised exercise program: HIIT (n = 24) or RIT (n = 24). Serum hormone and metabolic parameters were measured at baseline and post-intervention. Age was included as a covariate in analyses due to between-group differences. CLINICAL TRIAL NUMBER: Not applicable.
resultsAfter 12 weeks, the HIIT group showed a significantly greater reduction in FAI and HOMA-IR compared with RIT (p < 0.05). Improvements in BMI, LH/FSH ratio, and fasting insulin were also more pronounced in the HIIT group. Bonferroni corrections and effect sizes (Cohen's d) were calculated for all multiple comparisons.
conclusionHIIT appears to exert superior effects on androgenic and metabolic profiles compared with RIT, suggesting its potential as an efficient, non-pharmacological intervention for PCOS management. The clinical significance of these findings supports incorporating structured HIIT protocols into individualized PCOS treatment strategies. CLINICAL TRIAL NUMBER: Not applicable.
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