Evidence map›Paper›PMID 42230670›Full record

ArticleNPJ vaccines2026

Schistosomiasis vaccine SchistoShield® induces functional immune memory responses in US and African populations.

Mumtaz Y Balkhi, Aravindan Kalyanasundaram, Aryandra Arya, Desalegn W Kifle, Mallory Mckinnon, Dinesh Krishnappa, Harshvardhan Shrivastava, Mohamadou Siribie, Asma Aziz, Hyonjin Jeon and 16 more

Abstract read
In one paragraph

Article in NPJ vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Mumtaz Y BalkhiDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Aravindan Kalyanasundaram *Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Aryandra Arya *Department of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Desalegn W KifleDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Mallory MckinnonDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Dinesh KrishnappaInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Harshvardhan ShrivastavaInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Mohamadou SiribieInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Asma AzizInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Hyonjin JeonInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Tanyada YongchaitrakulInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Birkneh T TadesseInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Njariharinjakamampionona RakotozandrindrainyMadagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar.
Ravomialisoa RazafimanantsoaMadagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar.
Henry Bere NoellieGroupe de Recherche Action en Santé, Ouagadougou, Burkina Faso.
Nebié Issa OuedraogoGroupe de Recherche Action en Santé, Ouagadougou, Burkina Faso.
Amidou DiarraGroupe de Recherche Action en Santé, Ouagadougou, Burkina Faso.
Sean A GrayPAI Life Sciences Inc, Seattle, WA, USA.
Rhea N ColerCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle Children's Hospital, Seattle, WA, USA.
Jinhee LeeQuratis Inc., Osong Bioplant, 625-19, Yeonje-ri, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea.
Raphaël RakotozandrindrainyMadagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar.
Sodiomon B SirimaGroupe de Recherche Action en Santé, Ouagadougou, Burkina Faso.
Lisa A JacksonKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Florian MarksInternational Vaccine Institute, SNU Research Park, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Darrick CarterPAI Life Sciences Inc, Seattle, WA, USA.
Afzal A SiddiquiDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Afzal.Siddiqui@ttuhsc.edu.

Funding

Leadership Group for the Infectious Diseases Clinical Research Consortium (IDCRCLG) - Momi-Vax DMID #21-0004 {Supplement #6}UM1AI148684 · NIAID · EMORY UNIVERSITY · PI DAVID S STEPHENS · 2020 to 2026
$77.2M
A Vaccine for Schistosomiasis, "SchistoShield"R44AI103983 · NIAID · PAI LIFE SCIENCES, INC. · PI CARTER, DARRICK ALBERT, SIDDIQUI, AFZAL A · 2016 to 2022
$5.5M
Co-targeting Ezh2 with PD1 to improve T cell exhaustion reversal and tumor responsesR43CA244048 · NCI · IT BIO, LLC · PI YASEEN BALKHI, MUMTAZ · 2019 to 2019
$225k
Bill and Melinda Gates Foundation INV-004809Bill & Melinda Gates Foundation INV-004809Gates Foundation INV-004809Horizon 2020 Framework Programme DLV-815643National Institute of Allergy and Infectious Diseases R44AI103983National Institute of Allergy and Infectious Diseases UM1AI148684NCI NIH HHS R43 CA244048NIAID NIH HHS R44 AI103983NIAID NIH HHS UM1 AI148684RIGHT Foundation RF-2021-V02Wellcome TrustWellcome Trust Grant # 218454/Z/19/Z)
6 · The paper itself

Abstract

Helminth parasites of the genus Schistosoma cause 290,000 deaths annually, mostly in tropical and subtropical regions. An estimated 250 million people are currently chronically infected with Schistosoma parasites, imposing a risk of new and recurrent infections in an additional 800 million people. SchistoShield

Identifiers

PMID42230670
PMCPMC13526879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.